intROduçãOEmbora estime-se que dois terços das mortes por acidente vascular cerebral (AVC) ocorram em países em desenvolvimento, informações sobre epidemiologia, manejo e prognóstico nestes países são escassas 1,2 . Nos últimos anos, o AVC tem sido identificado como a primeira causa de morte no Brasil 3,4 . Em estudos brasileiros, o tipo mais frequente de AVC é o acidente vascular cerebral isquêmico (AVCI) 5,6 . Complicações médicas intrahospitalares são comuns no AVCI e contribuem significativamente para a morbimortalidade desta doença. Foi estimado que 75% a 95% dos doentes apresentem ao menos uma complicação após um AVCI, sendo que 24% desses pacientes apresentam alguma complicação que requer um tratamento imediato ou resulta em aumento do tempo de internação ou óbito [7][8] .Os objetivos deste trabalho foram: analisar as complicações e o tempo de internação de doentes internados por AVCI na fase aguda ou subaguda em uma enfermaria de neurologia geral; investigar a influência de idade, fatores de risco para doença vascular, território arterial acometido e etiologia sobre as complicações e o tempo de internação.

-Objective:To describe characteristics and provision of care for patients admitted with cerebrovascular disorders (CVD), focusing on ischemic stroke (IS), in a large, public, academic hospital in São Paulo, Brazil. Method: We retrieved information about 357 patients with CVD admitted to the Neurology Emergency Department (NED) and Neurology Ward (NW) of our institution. We described patient characteristics and management of IS in NED and in NW. Results: IS was diagnosed in 79.6% of CVD patients admitted to NED; 2.7% were submitted to thrombolysis. Extent of IS investigation and management were significantly different in NED and NW. Conclusion: IS patients in our center were younger than in developed countries. IS management was significantly influenced by patient characteristics. This information can aid in planning strategies to decrease stroke burden.KEy WorDS: stroke, diagnosis, thrombolytic therapy, emergency treatment. manejo do acidente vascular cerebral em um hospital universitário na maior cidade da américa do SulResumo -Objetivo: Descrever características e manejo de pacientes internados com diagnóstico de doença cerebrovascular (DCV), enfocando principalmente o acidente vascular cerebral isquêmico (AVCI), em um hospital público universitário em São Paulo. Método: Coletamos informações de 357 pacientes com DCV internados no Pronto-Socorro de Neurologia (PSN) e na Enfermaria de Neurologia (EN) de nossa instituição. Descrevemos características dos pacientes e manejo do AVCI no PSN e na EN. Resultados: o AVCI foi diagnosticado em 79,6% dos pacientes com DCV admitidos no PSN; 2,7% foram submetidos a trombólise. A extensão da investigação e o manejo da doença foram significativamente diferentes no PSN e na EN. Conclusão: os pacientes com AVCI em nosso centro foram mais jovens que em países desenvolvidos. o manejo do AVCI foi influenciado significativamente pelas características dos pacientes. Estas informações podem auxiliar no planejamento de estratégias para diminuir as conseqüências das DCV em nosso meio.PAlAVrAS-ChAVE: acidente cerebrovascular, diagnóstico, terapia trombolítica, tratamento de emergência.This study was performed in the

Although newer mutations on this and related disorders are continuously described, their clinical characterization has been restricted to the peripheral aspects of these conditions. A broader characterization of this rare disorder may contribute to better understand the mechanisms of the nociceptive and cognitive aspects of pain.

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OBJECTIVES: This study was undertaken to characterize the neuroinfection profile in a tertiary neurological ward.INTRODUCTION:Neuroinfection is a worldwide concern and bacterial meningitis, tetanus and cerebral malaria have been reported as the commonest causes in developing countries.METHODS:From 1999 to 2007, all patients admitted to the Neurology Ward of Hospital das Clínicas, S�o Paulo University School of Medicine because of neuroinfection had their medical records reviewed. Age, gender, immunological status, neurological syndrome at presentation, infectious agent and clinical outcome were recorded.RESULTS:Three hundred and seventy four cases of neuroinfectious diseases accounted for 4.2% of ward admissions and the identification of infectious agent was successful in 81% of cases. Mean age was 40.5±13.4 years, 63.8% were male, 19.7% were immunocompromised patients and meningoencephalitis was the most common clinical presentation despite infectious agent. Viruses and bacteria were equally responsible for 29.4% of neuroinfectious diseases; parasitic, fungal and prion infections accounted for 28%, 9.6% and 3.5% respectively. Human immunodeficiency virus (HIV), herpes simplex virus 1 (HSV1), Mycobacterium tuberculosis, Treponema pallidum, Taenia solium, Schistosoma mansoni, Cryptococcus neoformans and Histoplasma capsulatum were the more common infectious pathogens in the patients. Infection mortality rate was 14.2%, of which 62.3% occurred in immunocompetent patients.CONCLUSION:Our institution appeared to share some results with developed and developing countries. Comparison with literature may be considered as quality control to health assistance.