These guidelines on the use of radioiodinated (99m)Tc-MIBG scintigraphy in children, which summarise the views of the Paediatric Committee of the European Association of Nuclear Medicine, provide a framework which may prove helpful to nuclear medicine teams in daily practice. They have been influenced by the conclusions of the "Consensus Guidelines for MIBG Scintigraphy" (Paris, November 6, 1997) of the European Neuroblastoma Group and by those of the Oncological Committee of the French Society of Nuclear Medicine. The guidelines should be taken in the context of "good practice" and any local/national rules which apply to nuclear medicine examinations.
These guidelines, which summarise the views of the Paediatric Committee of the European Association of Nuclear Medicine, provide a framework which may prove helpful to nuclear medicine teams in daily practice. They contain information on the indications, acquisition, processing and interpretation of direct radioisotope cystography in children. The guidelines should be taken in the context of "good practice" and any local/national rules which apply to nuclear medicine examinations.
Scintigraphy using Tc-99m MDP and Tl-201 was performed in a patient with polyostotic Paget's disease and sarcomatous degeneration in the right iliac bone. Tc-99m MDP imaging showed abnormal uptake in both types of lesions. Tl-201 imaging showed increased uptake in the sarcomatous lesion and absent uptake in pagetic lesions. This result supports the idea that Tl-201 scintigraphy may have a potential role to play in the differentiation of Paget's disease from malignancy. To the authors' knowledge, Tl-201 has never been reported for the detection of sarcomatous change of pagetic bone.
This work aims at assessing the performance of a portable detection system, equipped with an NaI(Tl) scintillation detector for in vivo thyroid monitoring, which was properly calibrated using an anthropomorphic neck phantom. The anthropomorphic physical phantoms commonly used for the efficiency calibration of in vivo counters often present certain limitations regarding the geometry and the activity distribution. Therefore, the feasibility of these detection systems for in vivo monitoring should be assessed whenever possible. To accomplish this assessment, patients to whom (99m)Tc and (123)I marked radiopharmaceuticals have been administered in the framework of nuclear medicine diagnostic procedures were monitored. As the biokinetic models of the administered radiopharmaceuticals are known, the time-dependent activity functions in the critical organs after administration are easily quantified. The measured activities in the thyroid using the NaI(Tl) scintillation detector were compared with the estimated activities using the biokinetic models, in order to reach conclusion about the applicability of the portable scintillation counter for in vivo thyroid monitoring. The state-of-the-art Monte Carlo computer program PENELOPE and two voxel phantoms (male and female) were used to evaluate the overall uncertainties influencing the thyroid monitoring. A computational parametric study was performed to quantify the influence of several parameters in the activity quantification (neck-detector distance, thyroid shape, thyroid size and overlying tissue thickness), which allowed one to gain insight and to better understand the discrepancies between the calculated and measured activities.
Our objective was to assess the anxiety level in cancer patients undergoing nuclear medicine exams and to identify how professionals can improve patient experience. Methods: In total, 94 patients undergoing 99m Tc-hydroxymethylene diphosphonate ( 99m Tc-HDP) bone scintigraphy (BS) or 18 F-FDG PET/CT completed 2 scan-experience questionnaires and the Spielberger State Anxiety Inventory (STAI-S) before the scan and after image acquisition. Results: Before the exam, the mean anxiety levels were higher for the 99m Tc-HDP BS group than for the 18 F-FDG PET/CT group. After the exam, the opposite was true. Both groups experienced a reduction in anxiety after the scan (prescan score, 51.75 for 99m Tc-HDP BS and 44.67 for 18 F-FDG PET/CT; postscan score, 36.70 for 99m Tc-HDP BS and 38.82 for 18 F-FDG PET/CT). The greatest anxiety factor for the 99m Tc-HDP BS group was the duration of the exam (mean ± SD, 5.34 ± 2.08), whereas for the 18 F-FDG PET/CT group it was the result (5.40 ± 1.80). Conclusion: Patients undergoing nuclear medicine exams in an oncologic context had significant anxiety levels before and after their scans. However, 99m Tc-HDP BS and 18 F-FDG PET/CT had different triggers. It is of extreme importance that health-care professionals be aware of these peculiarities and adjust their procedures accordingly.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.