Aim: Many studies have showed that myalgia is a common onset symptom in coronavirus disease 2019 (COVID-19). This study aimed to determine the frequency of muscle pain in patients followed with COVID-19 diagnosis, and to investigate the relationship between muscle pain and creatine kinase (CK), pH, lactate and lactate dehydrogenase (LDH) levels. Material and Methods: One hundred ten patients diagnosed with COVID-19 in our hospital were included retrospectively in this study. Presence of myalgia at the time of admission and on the 14th day of control were investigated. The first admission laboratory findings, 3rd day CK values and 14th day control CK values of all patients were recorded retrospectively from their files. Results: The study included 110 patients diagnosed with COVID-19. Fifty patients (45.5%) had muscle pain at the time of admission, and it was one of the most common musculoskeletal complaints. High CK results were obtained in 48 (43.6%) of the 110 patients at the time of admission. Thirty-two (66.7%) of 48 patients with high CK had muscle pain (p<0.001). In the patients with muscle pain, the CK levels observed on 1 st , 3 rd , and 14 th day of the disease were found to be significantly higher than in those without muscle pain (p<0.001, p=0.003, p=0.029). No significant relationship was found between complaints of muscle pain and lactate, pH, and LDH values. Conclusion: Since some patients may only present with musculoskeletal symptoms such as myalgia, it is important that clinicians consider COVID-19 in patients presenting with myalgia and high CK levels.

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Stereoisomers of Salen-boron complexes with two equivalent stereogenic B-centers giving rise to diastereoisomers were assigned by CD and NMR spectra.

Objective:To describe the causes of intubation in patients who have been diagnosed with middle cerebral artery (MCA) infarction requiring mechanical ventilation (MV) by evaluating the clinical and radiologic features in the neurological intensive care unit (NICU). Materials and Methods:The patients with MCA infarction who required MV in the NICU were evaluated retrospectively. All patients' age, sex, risk factors of stroke, lesion topography, etiology and treatment of stroke, cause of intubation, percentage of extubation, death/discharge status were recorded. Results: It is found that between June 1 st , 2009, and December 31 st , 2015, 91 patients with stroke with MCA infarction were mechanically ventilated in the NICU. Fifty patients were intubated with neurologic causes and 40 patients needed intubation due to cardiopulmonary problems. One patient was treated in the NICU after surgery for a diaphragmatic hernia. Conclusion: The patients with MCA infarction who are followed up on a mechanical ventilator have poor prognosis. This group of patients constitutes elderly individuals who are at risk for vascular and organ failure. Their follow-up must be conducted in NICUs.Amaç: Nöroloji yoğun bakım ünitesinde (NYBÜ) mekanik ventilasyon (MV) gerektiren orta serebral arter (OSA) infarktı tanısı alan hastaların klinik ve radyolojik özelliklerini değerlendirerek entübe olma nedenlerinin tanımlanması amaçlanmıştır. Gereç ve Yöntem: NYBÜ'de MV gerektiren OSA infarktlı hastalar retrospektif olarak değerlendirildi. Tüm hastaların yaşı, cinsiyeti, inme risk faktörleri, lezyon topografisi, inmenin etiyolojisi, tedavisi, entübasyon nedeni, ekstübasyon yüzdesi, ölüm/taburculuk hali kaydedildi. Bulgular: 01.06.2009-31.12.2015 tarihleri arasında NYBÜ'de 91 OSA infarktı hastasına MV uygulandığı saptandı. Elli hastanın nörolojik nedenlerle ve 40 hastanın kardiyopulmoner nedenlerle entübe edildiği tespit edildi. Bir hastanın da diyafragma hernisine yönelik operasyon sonrası NYBÜ'de izlendiği saptandı. Sonuç: MV'de izlenen OSA enfarktı olan hastaların prognozu kötüdür. Bu hasta grubunu, vasküler ve organ yetmezlikleri açısından riskler taşıyan ileri yaşta bireyler oluşturur. Takiplerinin NYBÜ'lerde yapılması gereklidir. Anahtar Kelimeler: İskemik inme, mekanik ventilasyon, orta serebral arter, nöroloji yoğun bakım ünitesi Abstract Öz Ad dress for Cor res pon den ce/Ya z›fl ma Ad re si: Tuğçe Mengi MD,

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