No abstract

Pain is a common symptom associated with cancer and its treatment. Pain management is an important aspect of oncologic care, and unrelieved pain significantly comprises overall quality of life. These NCCN Guidelines list the principles of management and acknowledge the range of complex decisions faced in the management oncologic pain. In addition to pain assessment techniques, these guidelines provide principles of use, dosing, management of adverse effects, and safe handling procedures of pharmacologic therapies and discuss a multidisciplinary approach for the management of cancer pain.

Trigeminal neuralgia is an extremely painful condition. Treatment options for trigeminal neuralgia include anticonvulsants, opioids and surgical methods; however, some cases may be refractory to these therapies. In this article, the authors report a case involving a patient for whom conventional treatments failed; she underwent a successful trial of peripheral nerve stimulation and subsequently opted for a permanent implantation of an internal pulse generator, leading to long-term relief of her pain.

No abstract

End-of-dose failure was not observed based on the use of rescue medication after administration of single-entity, twice daily, hydrocodone ER capsules (Zohydro ER).