Malondialdehyde can be used as a marker of oxidative stress and a potential marker in predicting assisted reproductive techniques outcome.

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BackgroundPlatelet rich plasma (PRP) therapy is widely used in enhancing the recovery of skeletal muscle from injury. However, the impact of intramuscular delivery of PRP on hematologic and biochemical responses has not been fully elucidated in exercise-induced muscle damage. The purpose of this investigation the effects of intramuscular delivery of PRP on hematologic and biochemical responses and recovery strategy muscle damage induced by high intensity muscle exercise (exercise-induced muscle damage, EIMD).MethodsModerately active male volunteers participated in this study and were assigned to a control group (control, n = 6) and PRP administration group (PRP, n = 6). The subjects performed exercise with a load of 80% one repetition maximum (1RM) maximal voluntary contraction of the elbow flexors until point of exhaustion of the non-dominant arm was reached. The arms were treated with saline or autologous PRP post-24 h EIMD. Venous blood samples were obtained in the morning to establish a baseline value and 1–4 days post-exercise and were analyzed for serum ferritin, iron, iron binding capacity (IBC), creatinine kinase (CK), lactate dehydrogenase (LDH), aspartate aminotransferase (AST), and alanine aminotransferase (ALT).ResultsThe baseline levels of plasma iron, ferritin, IBC, CK, LDH, AST, and ALT were similar in both the control and PRP groups. However, 24-h following exercise a significant increase in these parameters was observed in both groups between 1 and 4 days during the recovery period. Interestingly, PRP administration decreased plasma iron levels compared to the control on the second day post-exercise. Plasma IBC increased in PRP group from Days 2 to 4 post-exercise compared to the control group whilst PRP administration had no effect on plasma ferritin, CK, AST, ALT, or LDH.ConclusionAcute exhaustive exercise increased muscle damage markers, including plasma iron, IBC, and ferritin levels, indicating muscle damage induced by exercise. PRP administration improves inflammation by reversing the increase in the iron levels post-exercise without displaying any myotoxicity and may have a role to play in the recovery of exercise-induced muscle damage.

Objective: Aim of this study was to evaluate possible effects of saliva and nasal secretion on some physical properties, such as sorption, solubility, surface hardness and colour change on four different resin-based materials over a certain time period. Materials and Methods: A total of 128 disc-shaped specimens with a diameter of 50mm and thickness of 0.5mm were tested to evaluate sorption and solubility (ISO-1567). The specimens were stored in different solutions prior to testing. Surface hardness measurements were performed by using a Vickers hardness testing machine. A total of 20 cylindershaped test specimens with a diameter of 13 mm and thickness of 1 mm were prepared to evaluate colour change (ΔE). Analysis of variance was used to determine significant differences among groups. Paired t and Tukey Post-Hoc tests were performed to investigate significant differences among subgroups at all time intervals (p<0.05). Results: It was found that while the percentage absorption value at T7(7 days) of the auto-polymerizing (A) groups storaged in artificial saliva + nasal secretion were the highest (0.057±0.119), the percentage absorption value at T15(15 days) of the D groups storaged in artificial nasal secretion were the lowest (0.013±0.09). Besides, it was found that the percentage solubility value at T30(30 days) of visible ligth-cusing resin (VLC) groups storaged in artificial nasal secretion were the highest (0.016±0.003), and the percentage solubility value at T1(1 day) of the D groups storaged in distilled water were the lowest (0.01±0.02). While the highest hardness value was of T0(Dry) in group heat-polymerizing (H) (36.19±1.35), the lowest hardness value was of T0 in group D (9.83±2.48). When E values analysed for each group, VLC group showed the highest values (23.78±5.05) (p<0.05), group D showed the lowest values (9.06±2.82) in time (between the T0 and T30). Conclusion: The new polyamide resin was observed to show better physical properties when compared with other materials.

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