The possibility of application of endovascular and two-stage combined revascularization of the penis in the arteriogenic ED treatment is shown. Twenty male patients with multifocal atherosclerotic lesions of the aorto-iliac-femoral segments underwent the analysis of the branching patterns of the IPA according to the classifcation by Adachi and Yamaki followed by the interventional endovascular intervention (angioplasty, stenting) of the iliac arteries. Seventeen patients underwent the unilateral and three patients – bilateral stenting of the common and external iliac arteries. Three patients out of the total number of the operated ones additionally underwent an open revascularization of the penis by epigastric-penic anastomosis. A complex preoperative examination of patients – candidates for revascularization of the penis for arteriogenic erectile dysfunction was performed and included ultrasound, МCT-angiography of the pelvic arteries, and electroneuromyographic examination of atherosclerotic lesions of the pool vessels of the inner pudental artery. Subsequently, endovascular and combined open revascularization operations were performed on the iliac and penis vessels. The erectile function improvement according to the IIEF-5 scale (8–12 scores before the operation vs 16–19 points after the operation) was noted in 1, 3, 6, 12 months (p< 0.05). Combined revascularization operations on the iliac and penis arteries (endovascular and open “bypass”) allow an adequate arterial blood perfusion to the penis in the steno-occlusive lesions of the pool vessels of the IPA affected by atherosclerosis.
Information and knowledge constantly accompany human life. They are the most important factors of development, in particular socio-economic. A lot of research is being done on the definition of these concepts, however even today a number of unresolved issues on them remained. Analyzing human activity, and not only it, we can conclude that in nature everything happens according to one technology, namely: first, the goal is formed, then the virtual achievement of the goal is substantiated (knowledge of how to solve the problem is created) and only at the third stage its materialization begins. The question arises, what is knowledge and why exactly knowledge materializes. By revealing the essence of knowledge, as well as analyzing the presence of a systemic relationship between information and knowledge, which we consider as a dialectical system, we can explore and formulate the basic difference between knowledge and information and make clarifications of what we mean by the term “ information” in the systemic interconnection between information and knowledge. Research will contribute to a change in human consciousness towards understanding and perception of a new process of introducing the energy paradigm of development, which requires the development of new rules for the functioning of society in all spheres of its existence: upbringing, education, management, rethinking the meaning of a human, etc.
In the scientific literature, there are many studies on filling content both in the field of systemic development and in the field of human creativity, but the problem of their general influence on the understanding of the system-creative principle of being (reality) in harmony with the laws of nature, which is possible attributed to the basic principle of socio-economic development. At the stage of introducing a knowledge-based economy, the dependence of human life on the laws of nature increases. The laws of nature are the highest reality of being, which is an integral system with a complex multi-level structural and functional organization, which is focused on the systemic creative interaction of a person with the environment. The creative activity of a person is always aimed at changing consciousness by understanding a fundamentally new development process, which provides for the development of appropriate fundamentally new rules for the functioning of society in all spheres of its existence: upbringing, education, management, rethinking the meaning of a person, etc.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.