ZIF-8 microcrystals demonstrate different degradation kinetics in water, PBS (pH 7.4), and PBS with lactic acid (pH 5.0).

No abstract

A model nanocomposite releases drug within 40 minutes under UV irradiation.

A planar memristor was fabricated by a hybrid method combining AFM patterning and inkjet printing.

Recombinant viral vectors represent one of the most promising platforms for creating a new generation of vaccines against tuberculosis. We constructed a vaccine candidate based on a cold-adapted influenza vector with a truncated NS1 protein containing an insert of tuberculosis ESAT-6 and Ag85A antigens. The recombinant virus possessed a cold-adapted and temperature-sensitive phenotype and was attenuated for mice when administered intranasally. Immunofluorescent staining and Western blot showed the expression of ESAT-6 protein in MDCK cells infected by recombinant virus. After intranasal administration to mice, the recombinant virus stimulated a specific anti-tuberculosis CD4 + Th1-type response with the formation of polyfunctional antigen-specific T cells.