of death after heart disease. A total of 6820 new cancer cases were registered by Jordan Cancer Registry in 2010, of these, 4921 cases (72.2%) were among Jordanians, and 1899 cases were non-Jordanians. Out of a total of 4921 new cases of cancer recorded amongst Jordanians in the 2010, of these, 2330 cases (48.1%) were males and 2519 cases (51.9%) were females (Jordan Cancer Registry, 2010). The rank order of the five most common cancers affecting Jordanians are: Breast, Colorectal, Lymphoma, Lung, and Prostate. The crude incidence rate of all cancer among Jordanians was 79.4 per 100,000 population (74.0 for males and 85.1S for females). The lung cancer agestandardized rate (ASR) for incidence/mortality in men (27.0/24.1) is substantially higher than women (4.1/3.7) (Ferlay et al., 2012).

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p = 0.041, respectively). p = 0.012). Smoking behavior had no influence on Cmax (p = 0.16),. In general, the pharmacokinetic parameters were characterized by considerable coefficient of variation (CV) = 37.9 %), (Tmax = 1.71 ± 1.15 h, CV = 67.2 %), CV = 36.7 %) and (t1/2e = 4.57 ± 3.15 h, CV = 68.9 %). Conclusion: Smoking behavior may not be a significant determinant of the pharmacokinetics of clopidogrel following oral administration of 600 mg dose in patients undergoing PCI.