SUMMARY OBJECTIVE Tumor budding is a parameter that is increasingly understood in colorectal carcinomas. We aimed to investigate the relationship between tumor budding, prognostic factors, and survival METHODS A total of 185 patients who had undergone colorectal surgery were observed. Tumor budding, the tumor budding score, and the relationship between these and prognostic factors, and survival investigated. RESULTS Tumor budding was found in 91 (49.2%) cases. The relationship between the tumor budding score and histological grade, lymphovascular invasion, perineural invasion, pathological lymph node stage, and mortality rates were significant. CONCLUSION In our study, the relationship between tumor budding and survival is very strong. Considering these findings and the literature, the prognostic significance of tumor budding becomes clear and should be stated in pathology reports.
İnsizyonel herniler, daha önce yapılmış olan abdominal operasyon kesilerinden oluşan fıtıklardır. Batın cerrahisinde cerrahi girişimlerden sonra karın duvarında sık görülen bir komplikasyondur. Değişik kaynaklarda farklı rakamlar verilse de insizyonel herni görülme sıklığı vertikal midline insizyonlarda %2,9, transvers insizyonlarda % 3.6 oranında görülmektedir. Abdominal cerrahi sonrası sık görülen insizyonel herni, önemli oranda morbidite ve iş gücü kaybına neden olur. Tek tedavi seçeneği cerrahidir.Bu retrospektif çalışmada amaç insizyonel hernilerde uyguladığımız cerrahi yöntemleri ve postoperatif takipteki verileri paylaşmaktır.Yöntemler: Bu çalışmada 2007-2011 yılları arasında tedavi edilen orta hat geniş insizyonel hernili 54 hastanın verileri retrospektif olarak incelenmiştir.Bulgular: Çalışmada postoperatif nükse sebep olan diyabet, KOAH gibi kronik hastalıklar, yaş, cinsiyet gibi kişisel faktörler ile birlikte insizyonel herni nedeniyle meshli onarım yapılan hastalarda meshin sağlam faysa üzerinde 5 cm altında ve 5 cm üzerinde yapılan dekolasyon sonrası yerleştirilmesi ile nüks, postoperatif seroma gelişimi, postoperatif dren alma ve postoperatif hastanede yatış süreleri karşılaştırıldı. 5 cm üzerinde yapılan dekolasyonda nüks oranı daha az görülürken; seroma gelişimi, hastanede yatış süresi ve dren alma sürelerinde anlamlı farklılık saptanmadı.Sonuç: Sonuç olarak karın ön duvarı dev insizyonel hernilerde herni kesesi etrafında 5 cm üzeri sağlam faysa diseksiyonu yapıp greft uygulamanın nüksü en aza indireceğini düşünmekteyiz.
Objective: Thyroid gland is an important endocrine gland and thyroid cancers (TC) are the most noteworthy disease of the thyroid gland. Although thyroid surgery is performed for most particularly for malignancy, thyroidectomies still maintain a large part of surgical operations. We aimed to investigate the incidence and subtypes of the thyroid cancers in present study, with our 10 years' experience of thyroid surgery. Methods: Data of patients who underwent thyroidectomy were retrospectively analyzed. The patients who underwent bilateral total thyroidectomy were included to the study. Patients' age, gender and histopathological results were recorded. According to the histopathological reports we divided the patients into two groups either as benign or malignant. Results: A total of 3632 patients were included in the study. 2999 (82.6%) patients were in benign group and 633(17.4%) patients were in malignant group. The subtypes of malignant tumors were papillary carcinoma in 591 (93.4%), medullary carcinoma in 16 (2.5%), follicular carcinoma in 14 (2.2%), oncocytic (hurtle cell) carcinoma in 7 (1.1%) and undifferentiated (anaplastic) in 5(0.8%) of the cases. Conclusion: Incidental thyroid cancers are not a rare entity after pathological examination of thyroid specimen after surgery. Therefore, we suggest careful evaluation and bilateral leb lobectomy ectomy in surgical treatment of thyroid conditions
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