Abstract Maternal mortality rate in Indonesia is still high enough which is dominated by three main causes of death that is bleeding, preeclampsia, and infection. Maternal Mortality in Samarinda city in 2015 increased by 76 per 100,000 live births. Maternal mortality in Samarinda city, dominated maternal death aged 20-34 years that fall into maternal and maternal death category. One of the causes of maternal death is preeclampsia and one of the causes of preeclampsia in pregnant women is obesity. The purpose of this study to determine the relationship of obesity with preeclampsia in pregnant women trimester II and III in RSUD Abdul Wahab Sjahranie Samarinda with specified α is 0,05The design of this study is cross sectional, sampling technique with purposive sampling of 39 pregnant women trimester II and III. The results of this study found there is a significant relationship between obesity with preeclampsia in pregnant women trimester II and III (p value = 0.006) with the value of α = 0.05.There is a significant relationship between obesity with preeclampsia in pregnant women trimester II and III in RSUD Abdul Wahab Sjahranie Samarinda 2018. Keywords : Obesity, Preeclampsia, Pregnant Women trimester II and III Abstrak Angka kematian ibu di Indonesia masih cukup tinggi yang didominasi oleh tiga penyebab utama kematian yaitu perdarahan, preeklampsia, dan infeksi. Kematian ibu di kota Samarinda tahun 2015 meningkat menjadi 76 per 100.000 kelahiran hidup hidup. AKI di kota samarinda, didominasi kematian ibu usia 20-34 tahun yang masuk dalam kategori kematian ibu hamil dan ibu bersalin. Salah satu penyebab kematian ibu adalah preeklampsia dan salah satu penyebab terjadinya preeklampsia pada ibu hamil yaitu obesitas. Tujuan penelitian ini untuk mengetahui hubungan obesitas dengan preeklampsia pada ibu hamil trimester II dan III di RSUD Abdul Wahab Sjahranie Samarinda dengan α yang ditentukan adalah 0,05Desain penelitian ini adalah cross sectional, Teknik pengambilan sampel dengan purposive sampling dan responden sebanyak 39 ibu hamil trimester II dan III. Hasil penelitian ini diperoleh terdapat hubungan bermakna antara obesitas dengan preeklampsia pada ibu hamil trimester II dan III (p value=0,006) dengan nilai α=0,05.Terdapat hubungan bermakna antara obesitas dengan preeklampsia pada ibu hamil trimester II dan III di RSUD Abdul Wahab Sjahranie Samarinda Tahun 2018. Kata Kunci : Obesitas, preeklampsia, wanita hamil trimester II dan III
Background: Breast milk spending is a very complex interaction between mechanics, nerves, and hormons. The decrease and production of breast milk production in the first days after delivery can be caused by a lack of stimulation of prolactin and oxytocin hormons. Caesarea section does not allow the mother to breastfeed her infant more flexibly, with adaptation to the pain, so she should be able to support the health worker thoroughly about the lactation process. Purpose: to know the difference of endorphin, oxytocin and combination effect on breast milk production in Postoperative section of caesarea section. Research design: quasi experimental design type post test only non equivalent control group design. The population in this study were all postoperative mothers caesarea section, 10 samples for each treatment. Group 1 : endorphin massage, group 2 (control) : the oxytocin massage, and group 3 : the combine massage. Results: Combination massage is the best method to produce the highest amount of ASI because the largest Sig p value is (1,000) where the level is significant <0.05. So H0 this study was rejected means that there is a significant difference between the production of breast milk from the combination massage compared with the two massage done separately. Conclusion: It is expected during childbirth the midwife can develop and implement independent non-pharmacological midwife actions to help increase milk production
Many mothers who give birth to Sectio Caesarea (SC) do not Initiate Early Breastfeeding (IMD), which fails exclusive breastfeeding. This study aimed to determine the effect of IMD management in postpartum SC mothers on nutritional status, speed of milk production, and quality of breast milk protein. Method: quantitative research with quasi approach experiment. The research design used was a pre-post-test control non-equivalent control group. A sampling of this study used the Consecutive method sampling with a sample of 20 mothers who gave birth by cesarean section (SC). Hypothesis testing uses the independent t-test and the Mann-Whitney test. The study results showed an influence on the management of IMD in postpartum SC mothers on the speed of ASI production (p-value=0.004) and nutritional status (p-value=0.028). There was no effect of IMD management on postpartum SC mothers on the quality of breast milk protein (p-value = 0.543). This study recommends that the hospital implement an IMD promotion program before the abdominal wall is closed as a form of intervention to increase milk production and maternal nutritional status
Introduction: Breast cancer or breast maligna is one of the second high death causes after heart coronary and tend to increase. Purpose of this study is to understand the risk factors of breast cancer in Dr.Kanujoso Djatiwibowo Balikpapan hospital. Methods: This study is quantitaive, analytic study with case control design and used Chi-Square, this study used 48 samples women with breast cancer (1:1) with purposive sampling. Bivariate analysis using chi-Square test, with OR (Odd Ratio or chance) using 95%confidence level. Results: The results showed a significant relationship between obesity (OR 11.7; p<0.001), hormonal family planning (OR=4.1; p=0.019), history of breastfeeding (OR=0.3; p=0.035) and family history (OR=4.5; p=0.017) with the incidence of breast cancer. Conclusion: obesity is the dominant risk factor where obese women are 11.7 times at risk of breast cancer.
Determining the effect of Bryophyllum pinnatum treatment in modulating immune response and the pregnancy outcomes of pregnant pristane-induced lupus mice model. Sixteen Balb/c mice were intraperitoneally injected with single 0.5 cc pristane to induce lupus manifestations. After 12 weeks of injection, mice were mated and considered as gestational day 0 (GD0). Mice were divided into 4 groups based on the dosages of Bryophyllum pinnatum: control (no treatment), B1 (10.5 mg/kg), B2 (21 mg/kg), and B3 (42 mg/kg). The treatment was given orally every day started from GD9 until 9 days. At the end of the study, blood pressure and fetal size were measured. Serum anti-dsDNA and urine albumin levels were measured by ELISA. Spleen T helper (Th) and mature B cells percentages were measured by flow cytometry. Administration of Bryophyllum pinnatum reduced the percentages of Th1 (p=0.006), Th2 (p=0.005), Th17 (p=0.000), and mature B cells (p=0.007) in dosedependent manner. B1 and B2 had significantly lower of systolic blood pressure compared to control (p=0.026 and p=0.022 respectively). Significantly lower of anti-dsDNA levels were found in B1 group compared to control (p=0.014). However, no significantly different of urine albumin levels were found between groups. Bryophyllum pinnatum also significantly increased the fetus body weight in dosedependent manner (p=0.000). Treatment of Bryophyllum pinnatum could improve the pregnancy outcome and modulate the immune response in pregnant pristaneinduced lupus mice. Therefore, Bryophyllum pinnatum is a potential herb, which can be developed as an immunosuppressive agent in the future.
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