From April 5th to 12th, 2020, between the 25th and 32nd days after the first COVID-19 case in Turkey, a self-administered online questionnaire (SurveyMonkey®) consisting of 90 questions was conducted for doctors and nurses that voluntarily participated in the study. We aimed to reduce the risk of bias in the questions posed to the participants by carrying out this retrospective study in the early phase of the COVID-19 outbreak. The first part of the questionnaire examined subjects such as demographic characteristics, occupational and institutional information, medical history,

We aim to evaluate the change in the diagnostic spectrum in dermatology outpatient applications compared to before COVID‐19. All patients were enrolled from the Department of Dermatology between February 12 and May 8, 2020, the duration of 4 weeks before COVID‐19 and 8 weeks after were analyzed in three parts consisting of 4 weeks. Data obtained from the database such as age, gender, diagnoses were anonymized. Repeated applications with the same diagnosis in 10 days after the first presentation were ignored. Compared to the pre‐outbreak, there was a 3.5‐fold decrease in dermatology applications in the first month after COVID‐19 and an 8.8‐fold in the second month. We found a significant increase in the frequency of diagnoses such as generalized pruritus, pityriasis rosea, alopecia areata, bacterial skin/mucosa diseases, and zona zoster after COVID‐19. The frequency declined in diseases such as verruca vulgaris, hyperpigmentation, skin tag, melanocytic nevus, and seborrheic keratosis/solar lentigo. It has been found that the frequencies of most diseases, including acne (⁓25% of patients), did not change. We think that many factors, such as affecting the quality of life, risk perception, increased stress burden may cause a change in the diagnostic distribution of the dermatology applications.

Coronavirus Disease-2019 (COVID-19) spread rapidly worldwide in about three months and was declared a pandemic by the World Health Organization on March 11, 2020. It was reported that more than 80 million people had been infected, and more than 1.8 million patients had died of COVID-19 by the end of December 2020. 1 Due to the rapid spread and fatal course of the infection, the search

Recurrent oral ulcers (ROUs) are the most common disorder of the oral cavity in the community. Although many etiological causes such as trauma, genetic, nutritional, infectious, immune, drug-mediated, rheumatological, endocrinological have a role, it is commonly idiopathic, known as recurrent aphthous stomatitis (RAS). 1-3 Indeed, RAS has accounted for 25% of oral ulcers in adults and 40% in children. 2 The most challenging issue for the clinician to deal with in the diagnosis is to distinguish whether oral ulcers are associated with primarily Behçet's disease (BD) and other systemic inflammatory processes such as inflammatory bowel diseases and connective

Purpose We aimed to reveal the relationship of serum uric acid (SUA) with monocyte‐high‐density lipoprotein ratio (MHR) and other inflammatory markers in acne patients before and after isotretinoin treatment. In this way, we can try to shed light on the relationship between isotretinoin treatment and atherosclerosis. Methods Two hundred twenty‐four acne patients who administered isotretinoin (0.5‐1 mg/kg/day) were enrolled in the study. In the pretreatment phase and 3 months after treatment, MHR, SUA, mean platelet volume, neutrophil‐lymphocyte ratio (NLR), platelet‐lymphocyte ratio, monocyte‐lymphocyte ratio, serum triglyceride, total cholesterol, high‐density lipoprotein (HDL), and low‐density lipoprotein (LDL) levels of the patients were analyzed. Results Compared to the pretreatment phase, three months after treatment, there was a statistically decrease in neutrophil count and an increase in lymphocyte count (p: 0.002, p: 0.011, respectively). Accordingly, there was a statistically significant decrease in NLR (p: 0.001). It was noteworthy that MHR and SUA levels increased significantly (p: 0.042, p: 0.010, respectively) and there was a positive correlation between SUA level and MHR (r: 0.212, p: 0.012). Serum total cholesterol, LDL, and triglyceride levels increased and HDL levels decreased significantly after treatment (p: 0.001). Conclusion This study contributes to the comprehension of the relationship between isotretinoin treatment and atherosclerosis, which has been frequently reported in the literature. It was thought that the isotretinoin‐induced SUA increase might be related to dyslipidemia. Isotretinoin may initiate the atherosclerotic process in vascular endothelial and smooth muscles, with SUA increase and HDL decrease. An increase in MHR is also an inflammatory marker indicating this process.

No abstract

Albendazole is a drug commonly used for treating many parasitoses. The primary mechanism of action is inhibition of microtubule polymerization binding to β-tubulin, similar to colchicine as a microtubule formation inhibitor. It is reasonable that these two antimitotic drugs can cause side effects such as alopecia and cytopenia by a similar mechanism. In the literature, only one albendazole-induced anagen effluvium has been reported. This article presents two cases of anagen effluvium that developed 2 weeks after oral albendazole administration, summarizes all cases reported to date, and offers recommendations for a diagnostic approach.

Özet AbstractInflammatory linear verrucous epidermal nevus (ILVEN) is a rare disease, occurring mostly at birth and adolescence, presents as erythematous and verrucous papules, which are pruritic and arranged in a linear array. Adult onset of the condition is very rare. ILVEN is a treatment-resistant disease. The lesions of the patient were presented at the age of 30 years and they were clinically and histopathologically consistent with ILVEN disease. Patient was treated with topical agents successfully. We presented the case since adult onset of ILVEN was seen rarely.