Corn silk (Stigma maydis) contains compounds that play a role in wound healing, such as flavonoids, saponins, tannins. This study aims to formulate a gel from corn hair extract and see its activity in healing burns. The test group was divided into four groups: group I (hot metal induction), group II (without extract ), group III (corn hair extract concentration 5%), and group IV (comparison B®), which metal induction. The parameters observed were % wound healing, epithelialization time, and histopathology. The results of the study on the average% of burns healing rate 7, 14 and 21 days, namely group I (27,92%; 62,42%; 100%), group II (35,39%; 60,16%; 100%), group III (44,05%; 63,69%; 100%) and group IV (32,81%; 66,48%; 100%). The mean time of tissue peeling epithelialization groups I, II, and III was on day 16, and group IV was on day 17. For the histopathological results, the mean score of collagen fibers, fibroblast cells, and epithelialization was respectively group I (2,2; 2,7; 2), group II (2,8; 2,9; 2), group III (3,3; 2,9; 2,7), and Group IV (3,9; 3; 3). The results of the two-way ANOVA statistical test on % burn healing (p> 0.05) and one-way ANOVA at the time of epithelialization (p> 0.05) and the histopathological score (p <0.05) showed that group III (the corn hair extract 5 %) could influence the process of healing burns. Keywords: Burns, Corn Silk Extract (Stigma maydis), % Burn Healing, Epithelialization Time, Histopathology
Conventional Nitrogen-Phosphorus-Potassium (NPK) fertilizer granules is absorbed by plants inefficiently. A certain proportion of the fertilizer is released into the environment. The aim of this research was to formulate NPK slow release fertilizer granules using polystyrene-poly 3-hydroxybutyrate polymers. NPK fertilizer granules were coated by spray coating method using polystyrene-polyhydroxybutyrate bioblend. NPK slow release granules obtained were evaluated in term of SEM and FTIR analysis; percentage of coating and released of P2O5; dissolution efficiency and rate of release of P2O5; and the order of release kinetics. FTIR analysis of slow release NPK fertilizer showed no chemical interaction between NPK fertilizer granules and coating polymer materials. The percentage of release of P2O5 from uncoated and coated NPK granules after 48 hours were 94.17 ± 7.88, and 46.45 ± 0.77%, respectively (p <0.05). The rate of release of P2O5 from uncoated and coated NPK fertilizer granules, was 1.90 ± 0.06, and 0.98 ± 0.01 %.h-1 respectively, (p <0.05). Kinetics release of slow release NPK fertilizer followed the Langenbucher kinetics (R = 0.993). The release efficiency of P2O5 from uncoated and coated NPK fertilizer granules were 65.67 and 33.66% (p <0.05), respectively. It can be concluded that coating of NPK fertilizer granule using poly-hydroxy butyrate could influence the rate and release efficiency of P2O5 (p<0.05).
Film soap is soap in the form of a thin layer having a thickness of 100 - 500 µm made of foaming film and plasticizer. The advantages of paper soap preparations are convenient in use, hygienic, practical, and easy to carry anywhere. Mesocarp red watermelon is a part of watermelon that contains flavonoid compounds that have antioxidant activity. The purpose of this study was to formulate the film soap of red watermelon mesocarp extract and to determine its antioxidant activity. In this study, the formulation was carried out by making four formulas with varying concentrations of ethanol extract mesocarp of red watermelon F0 = 0%; F1 = 1.5%; F2 = 2% and F3 = 3%. The evaluation was carried out in the form of organoleptic examination, pH, foam power, weight uniformity, moisture content, thickness, irritation test, stability and antioxidant activity tests. The evaluation results of the film soap from the four formulas were pH 9.29 - 9.12; weight uniformity 0.125 - 0.134 grams, water content 16.80 - 16.30%; thickness 0.14 - 0.15 mm and physically stable. The antioxidant activity of each formula was seen from the value, namely IC50F0 = 76.42µg / mL; F1 = 70.36 µg / mL; F2 = 65.14µg / mL; F3 = 62.14 µg / mL. From the research results, it can be concluded that the ethanol extract of red watermelon mesocarp can be formulated into film soap and has antioxidant activity which is included in the strong group.
Ethanol extract of guava leaf (Psidium guajava L.) contains flavonoids and tannins that are potentially as an antioxidant that may inhibit the activity of free radicals.The aim of this study is to formulate a body scrub cream from ethanol extract of guava leaf (Psidium guajava L.) and test their antioxidant activity.This study used three variations of concentration of ethanol extract 70% of guava leaf (Psidium guajava L.) i.e 1,5%, 2% and 2,5%.Body scrub creams are formulated into O/W type of creams by using guava seeds as a scrub.Evaluation of preparations included organoleptic examination, homogeneity, pH, cream type, stability test, particle size distribution, dispersion test and antioxidant activity test using DPPH method. The evaluation results showed that the physical properties of cream preparations provided good results and meet the requirements of cream preparations.The results of the antioxidant activity test found that the values of IC50 for each formula was F0 (without extract) 379,58 µg / mL, F1 (1,5%) 150,78 µg/mL, F2 (2%) 137,26 µg/mL and F3 (2,5%) 125,84 µg/mL.It can be concluded that body scrub creams of ethanol extract 70% of guava leaves (Psidium guajava L.) has the potential to be developed as a cosmetic preparation that can inhibit free radicals.
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