The rate of 5ƒ¿-reduction and 17ƒÀ-dehydrogenation of testosterone added in vitro, the activity of Na+, K+-insensitive ATPase, and the content of citrate were determined in the ventral prostate of rats of various ages and of castrated animals with and without testosterone replacement therapy.
It was confirmed that the nuclear testosterone 5ƒ¿-reductase was attached to membrane fraction as observed by Moore and Wilson (1972) in rat ventral prostate.
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