A case of angiostrongylosis is described in a 14-month-old golden retriever bitch. Conjunctival haemorrhage and neurological signs, referable to a space-occupying cerebral lesion, were associated with defective primary haemostasis caused by low levels of von Willebrand factor. Full clinical recovery followed treatment with desmopressin, fresh whole blood transfusion, fenbendazole and supportive care. The magnetic resonance image of the suspected organising haematoma is described. Similarities to the human condition, acquired von Willebrand syndrome, and a possible role for aberrant larval migration in haematoma formation are suggested.
A note on versions:The version presented here may differ from the published version or from the version of record. If you wish to cite this item you are advised to consult the publisher's version. Please see the repository url above for details on accessing the published version and note that access may require a subscription.For more information, please contact eprints@nottingham.ac.uk TITLE Alpha-chloralose poisoning in a cat SUMMARY A five-year-old domestic cat with acute unexplainable neurologic symptoms was presented for necropsy. Clinically, the cat showed an acute onset of ataxia, depressed mentation and continuous twitching/seizure activity in the morning after having been outside overnight. Despite immediate treatment, the cat progressed within twenty-four hours to a comatose state, opisthotonus and severe miosis unresponsive to light. Given a poor prognosis, euthanasia was elected. Gross findings were disappointing and consisted of a non-specific lung oedema and congested lungs and spleen. Surprisingly, within the stomach and intestines, fragments of cockshafers were found. Histologic examination confirmed the gross findings and additionally showed evidence of mild brain oedema, but failed to identify a cause for the severe clinical symptoms. In a final attempt to solve the case, a urine sample was tested for toxic substances and it was found to contain a significant amount of alphachloralose. This finding was unexpected.
BACKGROUNDThe cause of disease was unexpected in this case. Alpha-chloralose (AC) is used within and outside the UK to kill or immobilize pest animals. Cases of accidental AC poisoning in people are reported, whereas AC intoxication is only poorly described in pet animals. To the authors' knowledge, this report describes the first case of chloralose intoxication in a cat within the UK. Chloralose poisoning should be considered as differential diagnosis in cases with unexplainable neurological symptoms in animals and men.
GB, including the AHVLA's Veterinary Investigation Diagnosis and Analysis (VIDA) process. These threats are assessed by the CEG and potentially significant ones that could have an impact on our livestock industry are reviewed by the Veterinary Risk Group, a multiagency UK group that further assesses, characterises and ranks each threat through a standardised peer-reviewed riskbased approach. Thirdly, this ranking is used to inform the response required, including if there is a need for active surveillance, which is then developed. With respect to BVD, occurrence of BVD type 2 in the UK in 2007 prompted active surveillance which is ongoing, and the recent outbreaks in continental Europe confirm its value given continual trade. All of the samples submitted for testing with the AHVLA's PCR which can differentiate BVD-1,-2 and border disease, and all positive Erns antigen tests, are further screened by PCR to confirm the type. Further sequencing is only undertaken on an individual case basis. With regard to trade, non-notifiable endemic diseases remain the responsibility of the importer, who should take advice from their veterinarian about the potential risks to their herds (and beyond) from importation. Mr Kerby's initiative is very welcome, especially as the emphasis in surveillance in GB moves more towards a more collaborative approach.
An 8-year-old Jack Russell Terrier was diagnosed with hemolytic anemia caused by hemoplasmosis 4 years following splenectomy. Quantitative real-time PCR (qPCR) analysis was used initially to confirm infection with Mycoplasma haemocanis and subsequently to monitor and direct medical therapy. Doxycycline was administered beyond resolution of clinical signs until hemoplasma DNA could no longer be detected by qPCR. The dog remained clinically healthy and hemoplasma-negative 8 months following cessation of therapy. Canine hemoplasmosis should remain as a differential diagnosis for hemolytic anemia in dogs, particularly those that are splenectomized or immunocompromised, even in geographic regions where prevalence of infection is low. Prolonged doxycycline administration has been shown by qPCR to lead to sustained absence of detectable infection and should be considered as a first line treatment for canine hemoplasmosis.
Oedema associated with obstruction of the lymphatic pathways is termed lymphoedema. A number of cases of primary lymphoedema attributed to congenital lymphatic abnormalities have been reported in dogs. Cases associated with secondary or acquired lymphatic drainage failure are rare. This paper reports a dog with generalized peripheral oedema in which a presumptive diagnosis of secondary lymphoedema was made and discusses the causes, investigation and treatment of lymphoedema.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.