Aim: To evaluate the role of gray scale ultrasonography (US) and real time elastosonography (RTE) in carpal tunnel syndrome (CTS). Materials and methods: Both wrists of 18 healthy volunteers (n=36) formed the control group (Group 1) and 19 symptomatic outpatients of the neurology clinic constituted the patient group. According to nerve conduction study results, cases with mild CTS (n=15) formed Group 2; cases with moderate to severe CTS (n=20) formed Group 3. Cross sectional area (CSA) and strain ratio (SR) were measured at carpal tunnel inlet (CTI) and 4 cm proximal to the distal end of the radius (P). CSA and SR change score (CSA CTI -CSA P ; SR CTI -SR P ), CSA and SR ratio score (CSA CTI / CSA P ; SR CTI / SR P ) were calculated.
SummaryObjectives: Migraine is a headache disorder affecting approximately 12% of the population, predominantly female individuals. Migraine has been associated with vascular events such as stroke and cardiovascular disease. The close connection between these vascular disorders and atherosclerosis is well known. Carotid artery intima-media thickness (CAIMT) is a marker for detection of subclinical atherosclerosis. The present study is an analysis of the presence of subclinical atherosclerosis in migraine patients. Methods: CAIMT was evaluated in 25 female migraine patients and 27 female controls using innovative ultrasound (US) radiofrequency (RF) data technology. Mann-Whitney U test was used to compare measurements in patient and control groups. Results: There was a statistically significant difference between mean CAIMT of migraine patients and control group (p<0.005): mean CAIMT was 701±114 μm in migraine patients and 400±64 μm in control group. Conclusion: Migraine patients are more prone to atherosclerosis compared to healthy individuals. CAIMT measurement with sonography can be utilized in follow-up to detect subclinical atherosclerosis.Keywords: Carotid; intima-media thickness; migraine; ultrasound radiofrequency data technology. ÖzetAmaç: Migren, toplumun yaklaşık %12'sini ve ağırlıklı olarak da kadın bireyleri etkileyen bir baş ağrısı bozukluğudur. Migren, inme ve kalp-damar hastalığı gibi vasküler patolojiler ile ilişkilendirilmiştir. Bu vasküler bozukluklar ile ateroskleroz arasındaki yakın bağlantı iyi bilinmektedir. Karotis arter intima media kalınlığı, subklinik aterosklerozun saptanması için bir göstergedir. Biz bu çalışmada; migren hastalarında subklinik aterosklerozun varlığını incelemeyi amaçladık. Gereç ve Yöntem: Karotis arter intima media kalınlığı, 25 kadın migren hastasında ve 27 kadın kontrol grubunda yeni bir teknik olan ultrason radyofrekans-veri teknolojisi ile değerlendirildi. Hasta ve kontrol gruplarında fark varlığını analiz etmek için Mann-Whitney U testi kullanıldı. Bulgular: Migren hastaları ve kontrol grubu arasında ortalama karotis intima media kalınlığı açısından istatistiksel olarak anlamlı fark saptandı (p<0.005). Ortalama karotis intima media kalınlığı migren hastalarında 701±114 mikrometre iken kontrol grubunda 400±64 mikrometre ölçüldü. Sonuç: Migren hastaları, sağlıklı bireylere oranla ateroskleroza daha yatkındır. Sonografi ile karotis arter intima media kalınlığı ölçümü bu hastalarda subklinik aterosklerozun tanınması amacıyla takiplerde kullanılabilir.Anahtar sözcükler: Karotis; intima media kalınlık; migren; ultrason radyofrekans-veri analizi.
Background. Carpal tunnel syndrome (CTS) occurs as a result of compression of the median nerve at the wrist. The Quick Disabilities of the Arm, Shoulder, and Hand (QuickDASH) questionnaire is a selfadministered region-specific outcome instrument which measures symptom severity and functional status.
Direct oral anticoagulants (DOACs) have been shown to decrease the risk of ischemic stroke in non-valvular atrial fibrillation (NVAF). This study aims to investigate whether DOACs result in a significant change in lesion volume and the severity of the subsequent disability in patients who have experienced a stroke. Methods: The study included a total of 137 patients with NVAF and acute stroke. The cohort included 76 patients using DOACs, 21 patients using acetylsalicylic acid (ASA), and 40 patients with newly diagnosed atrial fibrillation (NDAF) who did not use antiaggregants or anticoagulants. Diffusion-weighted MRI was performed 6–12 hours after the first stroke symptoms and infarct volumes were measured by two independent observers. Baseline National Institutes of Health Stroke Scale (NIHSS) score, modified Rankin Scale (mRS) score at discharge and period of hospitalization were calculated. Results: When patients using DOACs due to NVAF and patients with NDAF were compared, the volumes of patients using DOACs (median 7.8 vs 23.1 cm 3 ; P ≤ 0.01) were statistically significantly smaller. However, there was no difference in volume between ASA users (median 16.9 cm 3 ; P = 0.16) and patients with NDAF. The DOACs group was significantly different compared to the NDAF group in terms of NIHSS scores (median 4.4 vs 8.3; P ≤ 0.01) and mRS scores at discharge (median 1.7 vs 2.7; P ≤ 0.01), and period of hospitalization (median 6.4 vs 10.4 days; P ≤ 0.01). Conclusion: We observe, while using DOACs, the infarct volumes of patients who experience stroke are smaller than those with NDAF and using ASA, as well as mRS scores at discharge are low and length of hospital stay is short.
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