No abstract

Cancer stem cells (CSCs) play a major role in local recurrence and metastatic spread in head and neck squamous cell carcinomas (HNSCC). Evidence suggests that cancer stem cells are resistant to conventional therapy. So the emerging concepts of the role of cancer stem cells in the pathobiology of HNSCC should be understood carefully to be able to create new paradigms in treatment plans.

No abstract

No abstract

Cherubism is a progressive, hereditary fibro-osseous lesion exclusively affecting the jaw bones. It is caused by the abnormal functioning of osteoblasts and osteoclasts, leading to replacement of normal bone by cellular fibrous tissue and immature bone, which produces painless progressive growth of the jaw, with a round facial appearance. It was first described in 1933 by Jones as ‘familial multilocular cystic disease of the jaws’. The term ‘cherubism’ was later coined to describe the rounded facial appearance resulting from jaw hypertrophy that was reminiscent of cherubs depicted throughout Renaissance art. The bony lesions generally occur at an early age, affect one or both jaws symmetrically, and grow progressively until puberty. Spontaneous regression is seen in most cases, although surgical re-contouring may be required for others for aesthetic reasons.

No abstract

How to cite this article: Rahman J, Routray S, Mishra SS, Mohanty I, Mohanty N, Sukla N. Knowledge, awareness, and practice of forensic odontology among dental surgeons in Bhubaneswar, India. J Unexplored Med Data 2017;2:26-33. Aim:The aim of the study was to evaluate knowledge, awareness, and practice related to forensic odontology among dental surgeons in Bhubaneswar, East India. Methods: A blind cross-sectional study, using a questionnaire with close-ended questions, was carried out. Interns were included to assess their knowledge and practice (related to dental record keeping) while in an institutional setting. In addition, dentists with Bachelor of Dental Surgery (BDS) and Master of Dental Surgery (MDS) qualifications (irrespective of their specialty) were assessed, which included purely private practitioners, purely academicians (dental surgeons teaching in dental colleges), and academicians-cum-practitioners. Results: The total forensic odontology knowledge, awareness, and practice score (based on summing all the positive responses --for all the relevant questions --and calculating the percentage) was 80%, 76%, and 84% for the MDS, BDS, and intern group, respectively. Conclusion: This study is the first of its kind to be undertaken in East India. The results show that there is an adequate level of knowledge and awareness regarding forensic odontology in all the groups investigated. Overall, the three groups also had adequate levels of good practice related to dental record keeping. However, regarding individual questions, there were some instances among the groups of inadequate levels of good practice. Key words:Forensic odontology, dental surgeons, East India, knowledge, awareness, practice, dental records ABSTRACTArticle history:

We present an extremely rare case of malignant peripheral nerve sheath tumour (MPNST) in a 30-year-old woman without associated neurofibromatosis 1. The patient presented with an 8 cm×4 cm lesion extending from 46 to the retro molar region involving the ramus of the right mandible associated with regional paraesthesia. Incisional biopsy revealed spindle cells with vesicular nuclei arranged in fascicles leading to a diagnosis of spindle cell lesion. Posterior segmental mandibulectomy was performed under general anaesthesia. On excisional biopsy, a definitive diagnosis of low-grade MPNST was established on the basis of immunohistochemistry. The patient was then lost to follow-up.