Rhinomaxillary Mucormycosis Masquerading as Chronic Osteomyelitis: A Series of Four Rare Cases with Review of Literature

Rhinomaxillary Mucormycosis with Palatal Perforation: A Case Report

“…As the disease progress to the orbit or skull, the patient may become confused and comatose. Fungal invasion of globe or retinal artery leads to blindness [8].…”

“…The low pH, hyperglycemic state and iron rich environment in diabetic patients favours the fungal growth. Mucormycosis is also caused by Rhizopus arrihzus species, in diabetic patients, due to their ability to produce enzyme Ketoreductase which allows them to utilize patient's ketone bodies for their nutrition [8]. Hematogenous spread occurs to other organs like brain or lungs leading to disseminated sepsis.…”

“…Hematogenous spread occurs to other organs like brain or lungs leading to disseminated sepsis. The disease is non-contagious and does not spread from person to person [8].…”

“…Most commonly used drug is Amphotericin-B deoxycholate with 80% of cure rate [1][2][3][4][5][8][9][10]. A new triazole derivative pasaconazole an oral antifungal agent has been used recently either alone or in combination with Amphotericin-B.…”

“…If the infection spreads to brain fatality rate exceeds more than 80%. Prognosis may improve with rapid diagnosis, early management and reversible underlying risk factors [8].…”