A primary pigmented neuroectodermal tumor of the uterine cervix is described. The patient was 57 years old when she presented with vaginal bleeding. She underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy and pelvic lymphadenectomy, followed by chemotherapy. Histologically, the tumor was characterized by the concomitant presence of two neural crest derivatives, neuroblasts and melanocytes. The latter cells were arranged in a tubulopapillary fashion and contained abundant melanin. Histochemical, immunohistochemical, and electron microscopic examination confirmed the diagnosis. The patient was alive without evidence of disease 5 years later. An origin of this tumor from abnormally migrated neural crest cells is suggested. Int J Surg Pathol 2(1): [31][32][33][34][35][36] 1994
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.