FUNDAMENTOS: Leishmaniose Tegumentar Americana é zoonose de manifestações clínicas variadas, em expansão no Brasil, sendo o estado de Mato Grosso do Sul importante área endêmica. OBJETIVOS: Avaliar clínica, epidemiológica e laboratorialmente pacientes com Leishmaniose Tegumentar Americana , atendidos no Hospital Universitário Maria Aparecida Pedrossian, Universidade Federal de Mato Grosso do Sul, Brasil (HU/UFMS). MÉTODOS: Trata-se de um estudo observacional do tipo transversal com abordagem descritiva e analítica. Foram avaliados, retrospectivamente, dados de pacientes suspeitos de Leishmaniose Tegumentar Americana , atendidos no HU/UFMS de 1998 a 2008, e encaminhados ao Laboratório de Parasitologia/UFMS para complementação diagnóstica. Para a inclusão neste estudo foram considerados critérios clínicos e laboratoriais. RESULTADOS: Quarenta e sete pacientes foram incluídos no estudo. Houve predominância de homens de 45 a 59 anos, com a forma cutânea, lesão única, ulcerada, em áreas expostas do corpo e com duração menor que seis meses. O comprometimento de mucosas foi crescente com o aumento da idade e maior em pacientes que procuraram atendimento tardiamente. Intradermorreação de Montenegro foi o exame de maior sensibilidade e o encontro do parasito mostrou-se mais difícil em lesões antigas. CONCLUSÃO: Suspeição diagnóstica precoce é de extrema importância para diagnóstico preciso. Associação de exame parasitológico e imunológico torna mais seguro o diagnóstico laboratorial.
Leiomyosarcoma is a rare skin tumor, most common in white men in the fifth to
eighth decades of life. Primary tumors are classified in dermal or subcutaneous,
that differ by clinical and prognostic features. They may appear on any site of
the body, but are rare on the face. A 54-year-old female was admitted with a 5cm
exophytic nodular lesion of 8 months duration on the right cheek, site of
previous chronic radiodermatitis. Histopathology revealed spindle-shaped cell
neoplasia, positive for smooth muscle actin on immunohistochemistry. Cutaneous
leiomyosarcomas on the face are rare and may occur in previously irradiated
areas. Immunohistochemistry is mandatory for an accurate diagnosis. Its
similarity with other tumors may complicate the diagnosis, with delay expansion
of the tumor.
Atypical mycobacteria are saprophytic organisms not transmitted from person to
person, which affect mainly immunosuppressed but also immunocompetent individuals. We
present a case of atypical mycobacteriosis after a vascular procedure, with
widespread cutaneous lesions associated with polyarthralgia. Mycobacterium chelonae
was identified by the polymerase chain reaction (PCR) method. The patient showed
improvement after treatment with three antibiotics. Mycobacterium chelonae causes
skin lesions after invasive procedures. The clinical form depends on the immune state
of the host and on the entry points. The diagnosis is based essentially on culture
and the mycobacteria is identified by PCR. We highlight the importance of
investigating atypical mycobacteriosis when faced with granulomatous lesions
associated with a history of invasive procedures.
Pigmented purpuric dermatoses are chronic vascular inflammatory conditions
characterized by the presence of pigmented macules. Among its different
presentations, lichen aureus is distinguished by the lichenoid conformation of
its plaques and the predilection for lower limb involvement. Its segmented form
is rare and difficult to control, especially in cases of symptomatic lesions. We
report a rare case of segmental lichen aureus with six years of evolution
associated with light itching. We also discuss the main therapeutic approaches
to control the disease.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.