Osteoporosis (OP) is a major global health concern, with aging being one of the most important risk factors. Osteoarthritis (OA) is also an age-related disorder. Patients with OP and/or OA may be treated surgically for fractures or when their quality of life is impaired. Poor bone quality due to OP can seriously complicate the stability of a bone fixation construct and/or surgical fracture treatment. This review summarizes the current knowledge on the pathophysiology of normal and osteoporotic bone healing, the effect of a bone fracture on bone turnover markers, the diagnosis of a low bone mineral density (BMD) before surgical intervention, and the effect of available anti-osteoporosis treatment. Interventions that improve bone health may enhance the probability of favorable surgical outcomes. Fracture healing and the treatment of atypical femoral fractures are also discussed.
The purpose of the study is to research and highlight modern achievements and prospects for the development of higher medical education in Ukraine. Theoretical and empirical methods were used to achieve the set goal and solve research problems. A modern doctor must perfectly master his professional competence. The main motive for reforming the medical field is the desire of students to master professional skills and practical skills, to deepen the acquired theoretical knowledge and apply it in practice, to develop skills regarding the standards of providing medical care, to gain experience in practical work, which will allow a modern student to successfully work independently in the future. It is also necessary to create a group that would carefully study and propose a number of conceptual priority measures related to changes in legislation and aimed at coordination between universities in order to develop a clear, unified strategy for reforming medical education, to ensure the responsibility of higher education institutions for the quality of education and its guarantee, taking into account the interests of society.
Aims: To determine an association between inflammatory and coagulation markers in a COVID-19 patient with ischemic stroke. Study Design: We performed a systematic review of 4 databases using the keywords “ischemic”, “stroke”, “COVID-19”,” Virus” Place and Duration of Study: December 2021 - January 2022. Methodology: Randomised control trials, observational studies, and systematic reviews were evaluated to ascertain the correlation between inflammatory and coagulation markers in COVID-19 patients with Ischemic stroke. Searches were conducted using Cochrane/EMBASE, PubMed/Medline, and PEDro between (2020-2021). Results: Of the inflammatory markers, white blood cells (WBC) and platelets did not vary considerably outside their normal ranges. All markers of hypercoagulability were elevated, but only Prothrombin Time corresponded with C-reactive protein (CRP). Conclusion: Inflammatory markers were not useful in forecasting the development of acute ischemic stroke, but CRP levels may be a possible marker to further research. D-dimer is a tried and true lab test that should be part of management guidelines in the ongoing COVID pandemic.
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