Severe coronavirus disease 2019 (COVID-19) infection leads to multifactorial acute respiratory distress syndrome (ARDS), with little therapeutic success. The pathophysiology associated with ARDS or post-ARDS is not yet well understood. We hypothesize that amyloid formation occurring due to protein homeostasis disruption can be one of the complications associated with COVID-19-induced-ARDS.
Nanoparticle-based drug delivery systems for crossing blood-brain-barrier employ diverse strategies. Coating of the nanoparticles with non-ionic surfactants is often employed for enhancing the delivery process. Polysorbate 80 is one of...
AbstractWe have developed Fullerene-C60 nanoformulations containing discrete sized nanoparticles by dispersing concentration range of Fullerene. Small sized particles are cytotoxic while larger ones are cell proliferative. The cell proliferative property is used for tissue repair in cellular and animal wound models.
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