Abstract-Fundamental frequency (F0) is one of the essential features in many acoustic related applications. Although numerous F0 detection algorithms have been developed, the detection accuracy in noisy environments still needs improvement. We present a hybrid noise resilient F0 detection algorithm named BaNa that combines the approaches of harmonic ratios and Cepstrum analysis. A Viterbi algorithm with a cost function is used to identify the F0 value among several F0 candidates. Speech and music databases with eight different types of additive noise are used to evaluate the performance of the BaNa algorithm and several classic and state-of-the-art F0 detection algorithms. Results show that for almost all types of noise and signal-to-noise ratio (SNR) values investigated, BaNa achieves the lowest Gross Pitch Error (GPE) rate among all the algorithms. Moreover, for the 0 dB SNR scenarios, the BaNa algorithm is shown to achieve 20% to 35% GPE rate for speech and 12% to 39% GPE rate for music. We also describe implementation issues that must be addressed to run the BaNa algorithm as a real-time application on a smartphone platform.

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Early detection of lung cancer is crucial in reducing mortality. Magnetic resonance imaging (MRI) may be a viable imaging technique for lung cancer detection. Numerous lung nodule detection methods have been studied for computed tomography (CT) images. However, to the best of our knowledge, no detection methods have been carried out for the MR images. In this paper, a lung nodule detection method based on deep learning is proposed for thoracic MR images. With parameter optimizing, spatial three-channel input construction, and transfer learning, a faster R-convolution neural network (CNN) is designed to locate the lung nodule region. Then, a false positive (FP) reduction scheme based on anatomical characteristics is designed to reduce FPs and preserve the true nodule. The proposed method is tested on 142 T2-weighted MR scans from the First Affiliated Hospital of Guangzhou Medical University. The sensitivity of the proposed method is 85.2% with 3.47 FPs per scan. The experimental results demonstrate that the designed faster R-CNN network and the FP reduction scheme are effective in the lung nodule detection and the FP reduction for MR images.

As an essential approach to understanding human interactions, emotion classification is a vital component of behavioral studies as well as being important in the design of context-aware systems. Recent studies have shown that speech contains rich information about emotion, and numerous speech-based emotion classification methods have been proposed. However, the classification performance is still short of what is desired for the algorithms to be used in real systems. We present an emotion classification system using several one-againstall support vector machines with a thresholding fusion mechanism to combine the individual outputs, which provides the functionality to effectively increase the emotion classification accuracy at the expense of rejecting some samples as unclassified. Results show that the proposed system outperforms three stateof-the-art methods and that the thresholding fusion mechanism can effectively improve the emotion classification, which is important for applications that require very high accuracy but do not require that all samples be classified.We evaluate the system performance for several challenging scenarios including speaker-independent tests, tests on noisy speech signals, and tests using non-professional acted recordings, in order to demonstrate the performance of the system and the effectiveness of the thresholding fusion mechanism in real scenarios.

Automatic segmentation of esophageal layers in OCT images is crucial for studying esophageal diseases and computer-assisted diagnosis. This work aims to improve the current techniques to increase the accuracy and robustness for esophageal OCT image segmentation. A two-step edge-enhanced graph search (EEGS) framework is proposed in this study. Firstly, a preprocessing scheme is applied to suppress speckle noise and remove the disturbance in the esophageal structure. Secondly, the image is formulated into a graph and layer boundaries are located by graph search. In this process, we propose an edge-enhanced weight matrix for the graph by combining the vertical gradients with a Canny edge map. Experiments on esophageal OCT images from guinea pigs demonstrate that the EEGS framework is more robust and more accurate than the current segmentation method. It can be potentially useful for the early detection of esophageal diseases.

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The fact that emotions play a vital role in social interactions, along with the demand for novel human-computer interaction applications, have led to the development of a number of automatic emotion classification systems. However, it is still debatable whether the performance of such systems can compare with human coders. To address this issue, in this study, we present a comprehensive comparison in a speech-based emotion classification task between 138 Amazon Mechanical Turk workers (Turkers) and a state-of-the-art automatic computer system. The comparison includes classifying speech utterances into six emotions (happy, neutral, sad, anger, disgust and fear), into three arousal classes (active, passive, and neutral), and into three valence classes (positive, negative, and neutral). The results show that the computer system outperforms the naive Turkers in almost all cases. Furthermore, the computer system can increase the classification accuracy by rejecting to classify utterances for which it is not confident, while the Turkers do not show a significantly higher classification accuracy on their confident utterances versus unconfident ones.

Background Cancer has become the second leading cause of death globally. Most cancer cases are due to genetic mutations, which affect metabolism and result in facial changes. Objective In this study, we aimed to identify the facial features of patients with cancer using the deep learning technique. Methods Images of faces of patients with cancer were collected to build the cancer face image data set. A face image data set of people without cancer was built by randomly selecting images from the publicly available MegaAge data set according to the sex and age distribution of the cancer face image data set. Each face image was preprocessed to obtain an upright centered face chip, following which the background was filtered out to exclude the effects of nonrelative factors. A residual neural network was constructed to classify cancer and noncancer cases. Transfer learning, minibatches, few epochs, L2 regulation, and random dropout training strategies were used to prevent overfitting. Moreover, guided gradient-weighted class activation mapping was used to reveal the relevant features. Results A total of 8124 face images of patients with cancer (men: n=3851, 47.4%; women: n=4273, 52.6%) were collected from January 2018 to January 2019. The ages of the patients ranged from 1 year to 70 years (median age 52 years). The average faces of both male and female patients with cancer displayed more obvious facial adiposity than the average faces of people without cancer, which was supported by a landmark comparison. When testing the data set, the training process was terminated after 5 epochs. The area under the receiver operating characteristic curve was 0.94, and the accuracy rate was 0.82. The main relative feature of cancer cases was facial skin, while the relative features of noncancer cases were extracted from the complementary face region. Conclusions In this study, we built a face data set of patients with cancer and constructed a deep learning model to classify the faces of people with and those without cancer. We found that facial skin and adiposity were closely related to the presence of cancer.