Copper oxide is a p-type semiconductor which has many applications in a different field. Copper oxide has excellent applications as an antioxidant, antibacterial, and antitumor or anticancer. Copper oxide nanoparticle combines with the cell membrane and enters into a cell; generate reactive oxygen specie (ROS), which causes oxidative stress in the cell. Oxidative stress leads to metastasis, cancer proliferation, apoptosis, DNA damage, cytotoxicity, and unregulated cell signaling. Hydroxyl free radical generated by Nanoparticles, combined with DNA and yield 8-hydroxyl-2-deoxyguanosine (8-OHdG), resultantly DNA is damaged. CuO nanoparticle shows antibacterial activity on different bacterial strains such as staphylococcus aureus, bacillus circulens BP2, Escherichia coli, and P. aeruginosa. Recently, CuO nanoparticles have applications in the detection of Cholesterol, lactate biosensor, DNA sequencing of microbe, and anti-HIV drug analysis. There is specialized CuO nanoparticle such as Glucose sensor, Hydrogen peroxide sensor, Immunosensor, Dopamine sensor for the detection of the different biomolecule. ROS generated by CuO nanoparticle causes toxicity, which leads to cell death. There is a fascinating area of research against tumors by nanoparticle use because of its antitumor nature. Metal nanoparticle exhibits anticancer activity due to physicochemical properties as antioxidant action or use of external stimuli. Free radical which are produced by the metal nanoparticle, kill cancer cells.
The present study aimed to identify the potential of modified nanoreinforcement (multiwalled carbon nanotubes; m-MWCNTs) to attenuate the thermal transport/decomposition/transition and mechanical aspects of three different polymeric matrices. In order to develop strong interfacial interaction between the host matrix and the incorporated nanotubes, 3-aminopropyletrimethoxy silane (APTMS) was used to m-MWCNTs. IR spectra confirmed the silane chemical moiety attachment on the upper surface of the MWCNTs. Conventional elastomeric mixing techniques were adopted to disperse m-MWCNTs within the three polymeric matrices (Acrylonitrile butadiene rubber, Silicone rubber, and Styrene Butadiene rubber) separately. SEM images assured the uniform dispersion of m-MWCNTs within the host polymeric matrices. Experimental evaluation of thermal conductivity revealed the reduction of thermal transport through the developed composite specimens by increasing the host polymer matrix to nanofiller concentration (m-MWCNTs). The utmost insulation effect was perceived in the F-MWCNTs incorporated silicone rubber nanocomposite comparatively. Glass transition/crystallization temperatures of the nanocomposites were lessened however melting temperatures were enhanced by impregnating nanotubes into the host polymeric matrices. Maximum thermal stability improvement due to the addition of m-MWCNTs was observed in the silicone elastomeric nanocomposite as compared to the other two systems. Proper dispersion and compatibility of m-MWCNTs with the polymeric matrices effectively enhanced the ultimate tensile strength (UTS)/elongation at break along hardness of rubber of the nanocomposites. The insulation character of m-MWCNTs/silicone rubber system was found best among the explored nanocomposite formulations.
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