In this study, antioxidant, oxidant and oxidative stress index of Thymbra spicata L. collected from Duhok (Iraq) region were determined. The aerial parts of the plant were extracted with ethanol. Rel Assay Diagnostics kits were used for detect TAS, TOS and OSI values. As a result of the studies, it was determined that TAS value of plant extract was determined 8.399±0.102, TOS value was 6.530±0.115 and OSI value was 0.078±0.001. As a result, it was determined that T. spicata has high antioxidant potential and in this context, can be used as a natural resource.

The present study aimed to determine antioxidant and antimicrobial activities of Salvia multicaulis Vahl plant collected in Gaziantep province, Turkey. Total antioxidant status (TAS), total oxidant status (TOS) and oxidative stress index (OSI) were determined using Rel Assay kits. Antimicrobial activity was determined with modified agar dilution method. The findings demonstrated that S. multicaulis had high antioxidant activity. However, it is recommended to avoid excessive consumption of the plant due to high OSI. It was also determined that plant extracts possessed antimicrobial potential. As a result, it was determined that the plant can be used as a natural antioxidant and antimicrobial resource.

Plants have been used for centuries to treat various diseases. In this study, Marrubium globosum Montbret & Aucher ex Benth. plant was used as a material. The extract of the plant was extracted with the help of soxhlet device using ethanol, which is a good polar solvent, and Rel Assay kits were used to determine the oxidant and antioxidant levels in the plant extract. Antifungal and antibacterial activities of M. globossum were tested against standard bacteria and fungus strains by agar dilution method. As a result of the analysis, TAS value of plant extract was determined as 7.677±0.231, TOS value as 12.387±0.083 and OSI value as 0.162±0.004. In this context, it has been observed that the plant has an important antioxidant potential. In addition, the plant extract was found to be effective against test microorganisms at 50-200 μg/mL extract concentrations. As a result, it has been determined that M. globossum can be a natural antioxidant and antimicrobial source.

The present study aimed to determine the total antioxidant status, total oxidant status and oxidative stress index of the ethanol extracts obtained from the fruits of Rosa canina L. plant collected in Erzincan province (Turkey). In this context, the fruit samples of the plant were extracted with ethanol (EtOH) using a Soxhlet device. Total antioxidant status (TAS), total oxidant status (TOS) and oxidative stress index (OSI) were determined using Rel Assay kits. It was determined that the TAS value of the plant was 4.602 mmol/L, the TOS value was 6.294 μmol/L and the OSI was 0.138. As a result, R. canina exhibited high antioxidant activities.

In this study, antioxidant, antibacterial and antifungal activities of Silybum marianum (L.) Gaertn. collected from Duhok (Iraq) were determined. Ethanol, methanol and dichloromethane extracts of the fruit part of plant were obtained. Antioxidant potential was determined with TAS and TOS kits using ethanol extracts. Antibacterial and antifungal activity were determined using agar dilution method. Antibacterial activity was determined against 6 bacterial strains (Staphylococcus aureus, S. aureus MRSA, Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa and Acinetobacter baumannii). Antifungal activity was determined against Candida albicans, C. krusei and C. glabrata. As a result of the studies, it was determined that plant extracts have high antioxidant activity. It was also found to be effective against bacteria at 25-400 µg/mL concentrations. Plant extracts were found to be more effective against gram negative bacteria. It was found to be effective against Candida species at 400-800 µg/mL concentrations. As a result, it was determined that the fruit parts of plant could be a natural antioxidant and antibacterial source.

In this study, the antioxidant and antimicrobial potentials of the ethanol extract of the aerial parts of Lepidium spinosum Ard., which is distributed in many regions of the world, were determined. The aerial parts of the plant were dried, powdered and extracted with ethanol. Total antioxidant status (TAS), total oxidant status (TOS) and oxidative stress index (OSI) of the plant extract were determined using Rel Assay Diagnostics kits. Antimicrobial activities of the plant extract were determined against standard bacterial and fungal strains by agar dilution method. As a result of the studies, the TAS value of the plant extract was determined as 4.550±0.132, the TOS value as 12.610±0.221, and the OSI value as 0.277±0.007. In addition, it has been found to be effective at 25-200 µg/mL against standard bacterial strains and 100-200 µg/mL concentrations against fungal strains. As a result, it was determined that L. spinosum used in our study could be a natural antioxidant and antimicrobial source. In this context, it is thought that natural material may be used in pharmacological designs.

In this study, biological activities of endemic Ferulago platycarpa were determined.• In this study, TAS, TOS and OSI values of Ferulago platycarpa were determined for the first time.• In this study, Phenolic contents of Ferulago platycarpa were determined.

In this study, antioxidant, oxidant, antimicrobial, and antiproliferative activities of Asparagus acutifolius L. and Asparagus officinalis L., known for their nutritional properties, were determined. In this context, methanol (MeOH) and dichloromethane (DCM) extracts of plants were obtained. Total antioxidant status (TAS), total oxidant status (TOS), and oxidative stress index (OSI) were determined using Rel Assay kits. Antimicrobial activities of plant extracts were determined against the test microorganisms using the agar dilution method. Antiproliferative activity was tested on the lung cancer cell line A549. As a result of the studies, it has been determined that the plant species have high antioxidant potential. In addition, it was observed that the antifungal potentials of plant extracts are high. Antiproliferative activity was determined to be at high level in both plant species. As a result, it has been determined that A. acutifolius and A. officinalis have medical potential and can be used as natural agents in pharmacological designs.