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<p class="Abstract">The article discusses anti-oxidant oral glucose tolerance and anti-hyperglycemic potentials of <em>Syzygium calophyllifolium</em>. Extracts from successive solvent extraction were tested for the total phenolic, tannin, flavonoid content and free radical scavenging property using DPPH, ABTS⁺, phosphomolyb-denum, FRAP, superoxide and metal chelating assays. Ethyl acetate extract of bark responded well against DPPH (IC₅₀ 4.13), ABTS⁺ (36832.29 µM TE/ g extract),phosphomolybdenum (100.4 g AAE/100g extract), superoxide and metal ion radicals. The methanol extract of bark was also found as an effective radical scavenger. The leaf methanol extract also showed significant anti-oxidant ability. The bark methanol extract could potentially reduce the blood glucose level in glucose loaded and diabetic rats. The immense anti-oxidant potential of <em>S. calophyllifolium</em> leaf and bark extracts could be taken as a good source of natural anti-oxidant supplement in food to defend oxidative stress related disorders like diabetes.</p><p> </p>

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