Objective: COVID-19 has affected millions of people throughout the world and due to the high rate of its spread, it is very vital to protect the people who are at the frontlines of COVID-19 positive cases. In this study, we have analyzed the level of awareness among the Healthcare Workers (HCWs) and level of preparedness by the Healthcare Authorities (HCA) for the safety of HCWs. Study Design: Cross-sectional prospective study. Subjects and Methods: Study was conducted online, for 3 months, from July to September 2020, at various Health Care Facilities (HCF) of Sindh, Pakistan. The survey instrument was circulated among the HCWs and a total of 419 filled forms were received and analyzed using SPSS 24. Results: Out of 419 participants, 54.4% were male and 45.6% female. Half of the respondents were doctors (50.1%) with majority having 1-5 years (61.6%) of experience. It was found that the major sources of information of HCWs about COVID-19 was social media (80.4%) and only 18.6% of HCWs had trainings to deal with pandemics. HCA couldn’t manage to maintain adequate supply of personal protective equipment (PPE) as goggle/eye shields were available only to 20.5% HCWs, shoe covers to 24.3%, N95 masks to 28.5%. Conclusion: We identified serious concern in the source of information but despite that the knowledge and awareness level was quite acceptable among our study respondents. However, greater efforts to be taken for training campaigns for HCWs as well as supply of PPE.

Background Anemia in pregnancy is a globally health-related issue, that affects both mothers and their newborn. Anemia during pregnancy across the world involves approximately 38% of the world population. To evaluate the effect of gestational anemia on perinatal outcome in the population. The aim of present study is to evaluate the effect of gestational anemia on perinatal outcome in the population of Hyderabad, Sindh, Pakistan. Methods A cross-sectional comparative analysis was conducted among pregnant mothers who were listed to give birth at Liaquat University of medical and health sciences Jamshoro/Hyderabad during the period of September 2018 to September 2019. The study population 400 were selected by convenient random sampling, and grouped into 2 on the basis of their Hb levels, with Hb < 11 gm% they were classified as anemic mothers, Hb ≥ 11 gm% were termed as non-anemic mothers, data was collected on the preformed questionnaire, and was analyzed on SPSS 21. Results The prevalence of anemia was 51.5% in in total population out of which, the incidence of normocytic normochromic anemia was highest 52.4 %microcytic hypochromic anemia was found in 19.4%, Overall, extremely low Apgar was found in 53 anemics, and 8 non. anemic mother’s infants, LBW incidence was 47.5 %; in anemic mothers, and 15.4 % in non-anemic group, the term, small for gestational age infants were 14.5% in anemic mothers, and 3.6% in non-anemic mothers, there were 36 preterm births to anemic mothers and 10 in non-anemic mothers. The incidence of caesarian section is 53.3% in anemic mothers compared to 30.9% in non-anemic mothers. Conclusions Anemia in pregnancy significantly increases risks of low Apgar, LBW, term SGA, preterm birth, and an increase incidence of caesarian section.

Aim: It is estimated that more than half a million of people die worldwide due to various incidences of intentional and unintentional poisoning and of them 84% occur in low- and middle-income countries. The clinical presentation of poisoning cases differs by age group, reason of poisoning, geographic region, substances involved and economic development of the country. The aim of present research was to estimate the incidence of poisoning in Shaheed Benazirabad based on above reasons. Study Design: Cross-sectional prospective study. Place and Duration of Study: Over a period of 6 months between July to December 2019 in a tertiary care hospital in Sindh, Pakistan. Methodology: Study was carried out by enrolling poisoned patients admitted in a tertiary care hospital. A standardized questionnaire was designed based on different variables in surveys conducted by American Association of Poison Control Centers. In total 263 poisoning cases were presented during the study period. The data obtained was coded, entered and analyzed using SPSS 24. Results: It was found that poisoning was more common in male (58.9%) in the age group of 16 to 30 years (48.7%) and single individuals (56.3%) with uneducated (55.1%) and jobless (54%) background. The common reasons of poisoning were suicide (36.5%) and substance involved in poisoning cases were pesticides (42.6%). Of the total cases reported during study period, 17.5% were admitted in Intensive Care Unit and death was reported in 5.3% of cases.  Conclusion: It was found that improved regulatory controls for hazardous chemicals, establishing poison control centers and decreasing exposure and reporting time can decrease poisoning cases.

Background: Hemophilia is a genetic disorder related to blood, in which the blood is impotent to clot the draining due to paucity of blood clotting factor. Objective: The dramatic theme of this research was to evaluate the knowledge skills about hemophilia in healthy individuals and cradle regarding familiarity of this ailment was also evaluated. Methods: Crossectional randomized research was conducted on 274 study subject’s normal population of rural areas of Sindh and frequent questions apropos cognizance of this disease were probed from all participants and SPSS software was used for the analysis of the data. Results: From the given data, it was estimated that 59% of the population were familiar with hemophilia, whereas 36% study subjects had no idea about this disease, feminine gender were more familiar with risk factors and people who had more knowledge about hemophilia were graduate in qualification. Chi Square value was found 0.001. Conclusion: It was concluded from the research that there should be promotional seminars should be conducted from health care providers regarding hemophilia and its risk factors.

Objective:To determine the effect of organophosphate poisoning (OPP) among patients at tertiary healthcare, Pakistan.Methods:This cohort study was conducted over a six-year period (January 2011 to December 2016) of OPP patients admitted to the intensive care unit of Peoples University of Medical & Health Sciences for Women SBA, Hospital Pakistan and their outcome was determined.Results:Total mortality was 17.39% (84 deaths in 483 patients, excluding those referred to Karachi). Out of these 84 deaths, 65 patients (13.46%) expired due to cardiorespiratory failure, 17 deaths (3.52%) followed due to complication of mechanical ventilation & ICU acquired infection and two deaths (0.41%) occurred due to renal failure. The major cause of poisoning was deliberate self-harm /suicidal intention (93.02%), with gender distribution of female (57.07%) and male (35.95%), followed by unintentional/accidental exposure (6.98%) in males. The intensive supportive treatment, precise and appropriate respiratory care, and adequate amount of atropine and pralidoxime doses are keys to reducing the OPP patient’s mortality.Conclusion:Organophosphate poisoning (OPP) intoxication is common in female gender. The easy availability of these harmful compounds has resulted in increased mortality either by accidental exposure or most often by the deliberate suicidal attempt.