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In this study, Pt-doped Bi2MoO6 nanocomposites were prepared by solvothermal and in situ reduction method. We used XRD, UV-Vis spectroscopy, TEM, EDS, and XPS to characterize its chemical properties. Results showed that the Pt-doped Bi2MoO6 nanocomposites had advantages of small size, good dispersion, and wide spectral response range. Then, we tested its biological toxicity and PDT efficiency on HL60 cells. Both pure Bi2MoO6 and Pt-doped Bi2MoO6 nanocomposites showed great biocompatibility after coincubated with leukemia cells for 12 h in the dark. As to PDT efficiency, Pt-doped Bi2MoO6 had a better-inactivated effect than pure Bi2MoO6. Furthermore, the PDT efficiency went up when atomic ratios and concentration increased. While the atomic ratio was 5% and the concentration was 1000 μg/mL, it reached the highest value at 85.2%. At last, we briefly analyzed the photocatalysis mechanism, which demonstrated that it was a potential photosensitizer with high efficiency for treating leukemia.

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We have successfully designed and synthesised a series of binary and ternary photocatalysts without noble metal cocatalysts for H2 generation by dispersing NiS2 and acetylene black nanoparticles on ultra-thin g-C3N4 nanosheets.

Titanium dioxide nanoparticles (TiO2-NPs) are highly efficient photosensitizers in traditional photodynamic therapy (PDT). The particle size of TiO2-NPs is small, only about 20 nm. However, the demands of ultraviolet light (UV) excitation feature shallow tissue penetration depth and may lead to severe tissue photon damage. Thus, in this research, TiO2-NPs are modified with semiconductor quantum dots (QDs) CdX (X = S, Te, Se) in various methods, such as ultrasonic, hydrothermal, sol-gel, aqueous phase, and hydrolysis precipitation. The transmission electron microscopy (TEM) images show that the size of CdSe-TiO2 is ranging from 6 to 14 nm. The ultraviolet-visible (UV-Vis) spectrum demonstrates that the CdX (X = S, Te, Se) modification can successfully extend the absorption range of TiO2-NPs into a different visible light region. CdSe QDs have the narrowest band gap compared with CdX (X = S, Te, Se) QDs. Visible light-activated CdSe-TiO2 nanocomposite shows the highest PDT inactivation efficiency toward HL60 cells compared with CdX-TiO2. The photogenerated carrier separation efficiency of CdSe-TiO2 nanocomposite is the highest shown in a fluorescence spectrum (FS). Furthermore, when conjugated with folic acid (FA), the prepared FA-CdX-TiO2 (X = S, Se) exhibits excellent cancer-targeting ability during PDT treatment. Optimum PDT efficiency of FA-CdSe-TiO2 indicates that photocatalytic and targeting ability is much higher than pure TiO2 and CdSe-TiO2. Our results provided a detailed investigation on the PDT performance of CdX (X = S, Te, Se) modified TiO2 and may act as a guide for further design of highly targeted performance visible-light response TiO2-NPs.