Bullous pemphigoid (BP) is an autoimmune, acquired, cutaneous disease caused by the
production of autoantibodies against hemidesmosomes' components in the basement
membrane. The estimated incidence in Europe ranges from 7 to 43 cases per million
inhabitants per year. Several studies have reported an association between BP and
neurological disorders (ND). Our cohort of Bullous pemphigoid and ND is the first in
Brazil and showed a significantly high prevalence of neurological and/or psychiatric
diseases, especially cerebrovascular accident (CVA) and dementia, in agreement with
the prevalence reported in several studies published in the medical literature in
recent years.
Pigmented Bowen's disease is rare, though more prevalent in men. It presents as a
well-delineated plaque in areas unexposed to sun. There are reports of association
with seborrheic keratosis, solar lentigo or exuberant pigmentation of genital and
intertriginous regions. A specific dermoscopy finding is the presence of brown or
gray dots in regular arrangement and coiled or dotted vessels. Thus, we aim to raise
awareness of the diagnosis of pigmented Bowen's disease in pigmented lesions.
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