The present study aimed to evaluate the enhancing effect of platelet-rich fibrin (PRF) on autogenous bone marrow aspirate (BMA) using in a resorbable matrix for repair of alveolar cleft defects. It was conducted on 12 patients (7 males and 5 females) with unilateral alveolar cleft and oronasal leakage. They divided into two random equal groups (group I and II). In group I, alveolar cleft defect packed with a mixture of PRF, β-Tricalcium phosphate, and BMA, and the same mixture without PRF for group II. Our clinical results revealed that, all patients had uneventful wound healing except some cases in group II. While, densitometric analysis showed a high statistical significant difference between two groups (p=0.011737) at 6 months interval but, at 12 months interval difference was not statistically significant (p=0.142480). Also, volumetric measurements of new bone showed that, there was highly statistical significant difference (p=0.037997) between group I and II at 12 month interval. The present study concluded that PRF may enhance the regeneration capacity of the stem cells when it added to BMA. Thereby, they may accelerate bone regeneration in alveolar cleft defects. Moreover, it may be used as membrane to cover grafted alveolar defect.

Aim:It is to assess TMJ functions after conservative treatment of unilateral subcondylar fractures. Subjects and Methods: A prospective study was conducted on 20 patients with unilateral mandibular subcondylar fracture undergoing nonsurgical treatment. Clinical and radiographic examinations were done prior to treatment and at 12-month follow up. Pain, perceived occlusion, mouth opening, protrusion, and horizontal movements of the mandible were evaluated by clinical examination. Radiologic evaluation was done using panoramic radiographs. Results: At 12-month follow-up, there was minimal pain in the temporomandibular joint region, there was an improvement in the perceived occlusion, without limited mouth opening. There was insignificant absolute difference between left and right lateral mandibular movements. The amount of increase in the protrusion of mandible was insignificant. On radiographic evaluation, mean ramus height pretreatment and 12 months post -treatment were 1.51+0.45 and 1.47+0.48, respectively. Conclusion: Unilateral subcondylar fractures of the mandible can be treated nonsurgically in patients with minimal occlusal discrepancies, adequate mouth opening, minimal displacement of condyle, and minimal ramus height shortening.

Aim: To compare socket bone preservation using Osteon II Collagen mixed with Hyaluronic Acid (Hy A) versus autologous concentrated growth factors enriched bone graft matrix (sticky bone) assessed by 3D cone beam computed tomography and histological evaluation .Patients and methods:30 patients were treatment planned for extraction of mandibular first molar teeth, leaving 30 sockets for the study. Sockets were divided randomly into two equal groups. Sockets were grafted as follows: Group (I) sockets were grafted by Osteon II Collagen mixed with Hy A, Group (II) sockets were grafted by sticky bone graft. A cone beam computed tomography (CBCT) radiographs at one day, 3 and 6 months were postoperatively done to assess bone density and tooth socket dimensions. Microscopic evaluation was performed at 6 months before implant insertion. All readings were recorded and analyzed statistically.Results: There is a high statistically significant difference between study groups as regards the mean values of bone density ,bone height, and percentage of volume change. In another the side ,other parameters showed insignificant differences between the study groups. Histological study referred to more maturation of bone in group I than group II. Conclusion:The results clearly concluded that both Osteon II Collagen mixed with HyA and sticky bone are successful in achieving clinical and 3D volumetric socket bone preservation with superiority for Osteon II Collagen mixed with Hy A.

The present study was designed to compare clinically and radiographicaly between immediate dental implant augmented with biphasic calcium phosphate (BCP) and it augmented with BCP coated with polylactide-co-glycolide (PLGA).This study was carried out on twenty adult male patients ,which were divided into two groups (group I included ten patients received immediate implant augmented with BCP ,while group II included ten patients were received immediate implants augmented with biphasic BCP coated with PLGA). Patients were evaluated clinically and radiographically to assess Gingival Index (GI) ,Probing pocket depth (PPD) , Marginal bone level (MBL), and Bone density measurement (BD) parameters at 3, 6, 9&12 months. Statistical analysis of GI and MBL results showed no significant difference in both groups at the different intervals while PPD results showed significant difference between both groups only at 9 and 12 months. On the same side, BD measurements showed statistical difference between groups at 3 month and highly statistical significant difference at 6, 9 and 12 months. The present study concluded that BCP coated with PLGA was significantly superior in comparison with BCP in augmentation of immediate dental implant.