Volumetric and histological evaluation of Osteon II Collagen with Hyaluronic Acid versus Sticky bone graft in Three Dimensional socket preservation

Abstract

Aim: To compare socket bone preservation using Osteon II Collagen mixed with Hyaluronic Acid (Hy A) versus autologous concentrated growth factors enriched bone graft matrix (sticky bone) assessed by 3D cone beam computed tomography and histological evaluation .Patients and methods:30 patients were treatment planned for extraction of mandibular first molar teeth, leaving 30 sockets for the study. Sockets were divided randomly into two equal groups. Sockets were grafted as follows: Group (I) sockets were grafted by Osteon II Collagen mixed with Hy A, Group (II) sockets were grafted by sticky bone graft. A cone beam computed tomography (CBCT) radiographs at one day, 3 and 6 months were postoperatively done to assess bone density and tooth socket dimensions. Microscopic evaluation was performed at 6 months before implant insertion. All readings were recorded and analyzed statistically.Results: There is a high statistically significant difference between study groups as regards the mean values of bone density ,bone height, and percentage of volume change. In another the side ,other parameters showed insignificant differences between the study groups. Histological study referred to more maturation of bone in group I than group II. Conclusion:The results clearly concluded that both Osteon II Collagen mixed with HyA and sticky bone are successful in achieving clinical and 3D volumetric socket bone preservation with superiority for Osteon II Collagen mixed with Hy A.

Effect of Osteontm Ii Collagen in The Treatment of Chronic Periodontitis Patients: A Clinical And Radiographical Study

“…In order to improve the osteoconductivity of the Osteon II material, bovine type I collagen was also added. Where, after assisting with the initial shape, the collagen is absorbed gradually over a few weeks (Abdullah et al, 2020). This was consistent with findings made by Bae et al, (2010) who discovered that the benefit of joining an insoluble HA with a resorbable β-TCP is that the slow-resorbing HA will retain volume while the faster-resorbing β-TCP will enhance bone regeneration.…”

“…It is an osteoconductive material that acts as a framework for the formation of bones. It has a similar linked porosity structure to human cancellous bone (Abdullah et al, 2020).…”

“…Numerous studies have demonstrated that HA/β-TCP can be used successfully as bone grafts (Lee et al, 2015). Bovine type I collagen was added to Osteon II to make it easier to manipulate and shape during the grafting operation, as well as to improve the osteoconductivity of the material (Abdullah et al, 2020).…”