The present study aimed to evaluate the enhancing effect of platelet-rich fibrin (PRF) on autogenous bone marrow aspirate (BMA) using in a resorbable matrix for repair of alveolar cleft defects. It was conducted on 12 patients (7 males and 5 females) with unilateral alveolar cleft and oronasal leakage. They divided into two random equal groups (group I and II). In group I, alveolar cleft defect packed with a mixture of PRF, β-Tricalcium phosphate, and BMA, and the same mixture without PRF for group II. Our clinical results revealed that, all patients had uneventful wound healing except some cases in group II. While, densitometric analysis showed a high statistical significant difference between two groups (p=0.011737) at 6 months interval but, at 12 months interval difference was not statistically significant (p=0.142480). Also, volumetric measurements of new bone showed that, there was highly statistical significant difference (p=0.037997) between group I and II at 12 month interval. The present study concluded that PRF may enhance the regeneration capacity of the stem cells when it added to BMA. Thereby, they may accelerate bone regeneration in alveolar cleft defects. Moreover, it may be used as membrane to cover grafted alveolar defect.
Aim. This prospective study was designed to evaluate three-dimensional (3-D) alveolar ridge augmentation through two stages surgical approach, using vertical alveolar distraction osteogenesis (VADO) followed by onlay sticky bone covered by collagen membrane, for augmentation of the atrophic alveolar ridge to facilitate implant installation. Subjects and Methods: Ten patients with atrophic alveolar ridge were treated by VADO. After bone consolidation the distractors were removed, implants were inserted, sticky bone graft was packed at buccal aspect, and covered by guided tissue regeneration (GTR) membrane. The implants were loaded after three months of its placement. Clinical evaluation was done to assess wound healing and implant stability. Also, the following parameters were evaluated on orthopantomography and cone-beam computed tomography; relapse in the distracted bone, crestal bone loss around the implant and bone density around the implant. All data was statistical analysed. Results: Mean vertical bone gain was 6.5 mm (range 5-8 mm), and the mean width gain was 4 mm ( range 3-5mm). There was 100% survival rate of all implants. There was significant decrease in the mean bone height throughout all periods. Also, significant improvement in bone density around the implant was reported along follow up periods. Conclusion: VADO followed by onlay sticky bone graft with GTR can be successfully performed to gain proper 3-D measurements of alveolar ridge that are essential for ideal implant installation in severe atrophic mandibular alveolar ridge.
Aim: To compare socket bone preservation using Osteon II Collagen mixed with Hyaluronic Acid (Hy A) versus autologous concentrated growth factors enriched bone graft matrix (sticky bone) assessed by 3D cone beam computed tomography and histological evaluation .Patients and methods:30 patients were treatment planned for extraction of mandibular first molar teeth, leaving 30 sockets for the study. Sockets were divided randomly into two equal groups. Sockets were grafted as follows: Group (I) sockets were grafted by Osteon II Collagen mixed with Hy A, Group (II) sockets were grafted by sticky bone graft. A cone beam computed tomography (CBCT) radiographs at one day, 3 and 6 months were postoperatively done to assess bone density and tooth socket dimensions. Microscopic evaluation was performed at 6 months before implant insertion. All readings were recorded and analyzed statistically.Results: There is a high statistically significant difference between study groups as regards the mean values of bone density ,bone height, and percentage of volume change. In another the side ,other parameters showed insignificant differences between the study groups. Histological study referred to more maturation of bone in group I than group II.
Conclusion:The results clearly concluded that both Osteon II Collagen mixed with HyA and sticky bone are successful in achieving clinical and 3D volumetric socket bone preservation with superiority for Osteon II Collagen mixed with Hy A.
INTRODUCTION Oroantral communication (OAC) with progressive formation of oroantral fistula (OAF) is one of the clinical complications encountered by oral and maxillofacial surgeons. There are several causes for OAC occurrence such as maxillary posterior teeth extraction, surgical removal of maxillary pathological lesions, and trauma (1, 2). When the OAF has been present for 3-4 weeks, or when its diameter is greater than 5 mm chance of spontaneous healing is less possible. If oroantral opening remains untreated, the escape of fluids, other mouth contents and oral bacteria into the maxillary sinus will be occurred leading to the patients experience chronic maxillary sinusitis (3,4). Various techniques and treatment modalities
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