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Soil salinity is not a recent phenomenon, it has been reported since centuries where humanity and salinity have lived one aside the other. A good example is from Mesopotamia where the early civilizations first flourished and then failed due to human-induced salinization. A publication 'Salt and silt in ancient Mesopotamian agriculture' highlights the history of salinization in Mesopotamia where three episodes (earliest and most serious one affected Southern Iraq from 2400 BC until at least 1700 BC, a milder episode in Central Iraq occurred between 1200 and 900 BC, and the east of Baghdad, became salinized after 1200 AD) have been reported. There are reports clearly revealing that 'many societies based on irrigated agriculture have failed', e.g. Mesopotamia and the Viru valley of Peru. The flooding, over-irrigation, seepage, silting, and a rising water table have been reported the main causes of soil salinization. Recent statistics of global extent of soil salinization do not exist, however, various scientists reported extent differently based on different data sources, such as there have been reports like, 10% of the total arable land as being affected by salinity and sodicity, one billion hectares are covered with saline and/or sodic soils, and between 25% and 30% of irrigated lands are salt-affected and essentially commercially unproductive, global distribution of salt-affected soils are 954 million ha, FAO in 1988 presented 932 million ha salt-affected soils, of almost 1500 million ha of dryland agriculture, 32 million ha are salt-affected. Precise information on the recent estimates of global extent of salt-affected soils do not exist, many countries have assessed their soils and soil salinization at the national level, such as Kuwait, United Arab Emirates, Middle East, and Australia etc. Considering the current extent of salt-affected soils the cost of salt-induced land degradation in 2013 was $441 per hectare, a simple benefit transfer suggests the current annual economic losses could be $27 billion.

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Plants subjected to abiotic stresses such as extreme high and low temperatures, drought or salinity, often exhibit decreased vegetative growth and reduced reproductive capabilities. This is often associated with decreased photosynthesis via an increase in photoinhibition, and accompanied by rapid changes in endogenous levels of stress-related hormones such as abscisic acid (ABA), salicylic acid (SA) and ethylene. However, certain plant species and/or genotypes exhibit greater tolerance to abiotic stress because they are capable of accumulating endogenous levels of the zwitterionic osmolyte-glycinebetaine (GB). The accumulation of GB via natural production, exogenous application or genetic engineering, enhances plant osmoregulation and thus increases abiotic stress tolerance. The final steps of GB biosynthesis occur in chloroplasts where GB has been shown to play a key role in increasing the protection of soluble stromal and lumenal enzymes, lipids and proteins, of the photosynthetic apparatus. In addition, we suggest that the stress-induced GB biosynthesis pathway may well serve as an additional or alternative biochemical sink, one which consumes excess photosynthesis-generated electrons, thus protecting photosynthetic apparatus from overreduction. Glycinebetaine biosynthesis in chloroplasts is up-regulated by increases in endogenous ABA or SA levels. In this review, we propose and discuss a model describing the close interaction and synergistic physiological effects of GB and ABA in the process of cold acclimation of higher plants.

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