Epilepsy is one of the main health problems in neurology that can lead to cognitive decline. Generally, the epilepsy-associated cognitive decline is influenced by demographic, clinical, and treatment characteristics. This study aimed to determine the characteristics of cognitive status of epilepsy patients who received monotherapy using first-generation antiepileptic drugs (AEDs), namely phenytoin, carbamazepine, and valproic acid. It involved 93 epilepsy patients of Mutiara Sukma Mental Hospital (n=38) and Mataram General Hospital (n=55). Besides, 93 healthy patients were assigned as healthy control group (HC) subjects (n=93). Demographic characteristics collected from epilepsy and HC groups were age, gender, and years of education. Clinical characteristics taken from both groups were MoCA-Ina score. Clinical characteristics taken from epilepsy group were age at epilepsy onset, type of seizure (partial vs generalized), etiology (idiopathic vs structural), first-generation AED used, years of treatment, and cognitive status. The result of the study revealed that there were no significant different between the two groups in the means of age and years of education as well as the frequency of male gender (p>0.05). The mean of MoCA-Ina score of epilepsy group was significantly lower compared with HC group (p<0.05). The frequency of cognitive decline among epilepsy patients was 75.3%. The cognitive functions of epilepsy patients using monotherapy with carbamazepine, phenytoin, or valproic acid was significantly lower compared with healthy subjects. We conclude that there was high prevalence of epilepsy-associated cognitive impairment which was associated with male gender.
Customer satisfaction survey for outpatient laboratory customer is routinely carried out in Clinical Laboratory InstallationRSUP Dr. Sardjito using modified SERVQUAL questionnaire. One advantage of using SERVQUAL is service provider will be able to monitorits service quality dynamics using standardized tool. Changes in one’s service quality can be measured using perceived quality changesbased on gap scorebetween different periods. All these years, RSUP Dr. Sardjito has not evaluated gap score changes in all survey period.This study aims to know service quality measured by perceived service quality on Customer Satisfaction Survey Period of Semester II2013 and Semester I 2014 by comparison. This is an observational non-experimental study using data from Customer SatisfactionSurvey in Clinical Laboratory Installation RSUP Dr. Sardjito Semester II 2013 and Semester I 2014. Data was analysed using SERVQUALmethod and presented descriptively as text and table. There were 231 and 229 responders respectively in Customer Satisfaction SurveySemester II 2013 and Semester I 2014. There were decreases in all but empathy service dimension. Decrease of expectation was foundin all SERVQUAL dimensions. The decrease of expectation exceeded perception decrease resulting in a rise of gap score from Semester II2013 to Semester I 2014 hence indicating an improvement of perceived service quality. There was an improvement of perceived servicequality according to external customer of Clinical Laboratory Installation RSUP Dr. Sardjito in Semester I 2014 compared to SemesterII 2013.
Latar Belakang: Stroke merupakan penyebab kecacatan dan kematian utama di dunia. Stroke iskemik merupakan subtipe stroke yang paling sering diderita. Pencegahan stroke iskemik dilakukan dengan menilai probabilitas terjadinya stroke iskemik seseorang dengan menggunakan Framingham stroke risk score. Faktor risiko lain untuk stroke iskemik yang perlu diperhatikan adalah penurunan kadar kolesterol HDL serum. Penelitian ini dilakukan untuk mengetahui hubungan antara kadar kolesterol HDL serum dan Framingham stroke risk score pada penduduk di Kecamatan Sekarbela Mataram.
Metode: Penelitian ini adalah penelitian deskriptif dengan rancangan cross sectional. Subjek pada penelitian terdiri dari 55 orang. Data karakteristik subjek yang ditunjukkan meliputi kadar kolesterol HDL serum dan berbagai faktor risiko dalam Framingham Stroke Risk Score disajikan dalam bentuk tabel.
Hasil: Penelitian ini diikuti 55 subjek dengan rerata usia 66,54 ± 7,816 tahun. Subjek dengan kadar kolesterol HDL serum rendah didapatkan sebesar 56,36% dengan proporsi tertinggi terdapat pada perempuan. Rerata tekanan darah sistolik subjek penelitian adalah 143,47 ± 25,54 mmHg. Proporsi subjek dengan penyakit diabetes melitus, penyakit kardiovaskular, hipertrofi ventrikel kiri, dan fibrilasi atrium tergolong rendah, sehingga rerata probabilitas risiko stroke iskemik yang didapatkan rendah yaitu 10,415%. Berdasarkan analisis Pearson didapatkan tidak adanya hubungan yang bermakna antara kadar kolesterol HDL serum dan Framingham stroke risk score (p>0,05).
Kesimpulan: Pada penelitian ini dapat disimpulkan bahwa kadar kolesterol HDL serum tidak berkorelasi dengan Framingham stroke risk score.
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