No abstract

No abstract

No abstract

Malaria is an endemic that often occurs in the coastal areas of East Lombok, West Nusa Tenggara. One of the most common ways of spreading this parasite is through asymptomatic malaria. Therefore, mass blood surveys and active case detection are needed to identify parasitemia and eradicate malaria in Batunampar village, Jerowaru subdistrict, East Lombok, West Nusa Tenggara, Indonesia. Mass blood survey was conducted on all residents of the research location through Rapid Diagnostic Tests, microscopic examination, and therapy. Furthermore, active case detection and evaluation were carried out for 5 consecutive years in collaboration with the Public Health Center in East Lombok. In the mass blood survey, 3,038 people (61%) were examined from a total of 5,017 residents. The Rapid Diagnostic Test (RDT) result showed that 15 people were positive for malaria, out of which 4 (27%) showed fever symptoms. Similarly, in the first year of active case detection, 296 residents suffered fever, with an Annual Parasite Incidence (API) decline below 1 per 10,000 population. The incidence of asymptomatic malaria in Batunampar village is 73%, which is relatively high. However, due to the successful detection of the associated parasite that causes this infection, it is easier to detect and treat sufferers, thereby reducing the rate of transmission. Detection of asymptomatic and symptomatic malaria and appropriate treatment are the keys to successfully eradicating malaria in Batunampar village, East Lombok.

Cartilage injury remains a major orthopedic challenge due to its low repair capacity, with the tendency to cause osteoarthritis. In addition, the treatment method involving platelet rich plasma (PRP) and platelet rich fibrin (PRF) as cartilage engineering components greatly anticipates promising recovery results. This research is aimed at determining the number of cells in platelet rich plasma (PRP) and platelet rich fibrin (PRF), particularly inflammatory cells. Blood specimens were collected from 30 rabbits that were divided into three treatment groups. The samples were then processed into control, PRP and PRF. This was followed by determining the number of cells in the form of platelets, leukocytes, lymphocytes, neutrophils and monocytes. According to the blood test results, the number of platelets increased by 3.8 and 4.5-fold in the PRP and PRF groups, respectively. Furthermore, 2 times (2.1-fold) increment was observed in leukocyte concentration for PRF, but zero in PRP. Conversely, the number of lymphocytes, neutrophils and monocytes decreased to 82, 72 and 40%, correspondingly, while PRP still showed no change. Based on the overall results and discussion, the number of platelets in both PRP and PRF increased severally, while leukocyte only occurred in PRF. This multi-fold expansion accompanied by growth factors has the capacity to accelerate cartilage recovery. Furthermore, the presence of inflammatory cells enhances the healing potential already existing in PRF.