Metal-organic framework (MOF)-derived hollow cobalt sulfides have attracted extensive attention due to their porous shell that provides rich redox reactions for energy storage. However, their ultradispersed structure and the large size of MOF precursors result in relatively low conductivity, stability, and tap density. Therefore, the construction of an array of continuous hollow cages and tailoring of the inner cavity of MOF-derived materials is very effective for enhancing the electrochemical performance. Herein, we in situ assembled small Co-based zeolitic imidazolate framework (ZIF-67) on the both sides of negatively charged MnO nanosheets to fabricate a hierarchical sandwich-type composite with hollow cobalt sulfide nanocages/graphene-like MnO. The graphene-like MnO nanosheets acted not only as a structure-directing agent to grow a ZIF-67 array but also as a promising electroactive material of electrochemical capacitors to provide capacitance. As an electrode material of supercapacitors, the as-prepared composites exhibit high specific capacitance (1635 F g at 1 A g), great rate performance (reaching 1160 F g at 10 A g), and excellent cycling stability (80% retention after 5000 cycles). The outstanding electrochemical properties of our designed materials can be attributed to the unique nanostructure that improved electrical conductivity, created more reactive active sites, and increased the diffusion pathway for electrolyte ions.

The efficiency of photon-to-electron conversion is extremely restricted by the electron-hole recombinant. Here, a new photoelectrochemical (PEC) sensing platform has been established based on the signal amplification of click chemistry (CC) via hybridization chain reaction (HCR) for highly sensitive microRNA (miRNA) assay. In this proposal, a preferred electron donor dopamine (DA) was first assembled with designed ligation probe (probe-N) via amidation reaction to achieve DA-coordinated signal probe (P-N). The P-N served as a flexible trigger to signal amplification through efficiently suppressing the electron-hole recombinant. Specifically, the P-N can be successfully ligated into the trapped hairpins (H1 and H2) via the superior ligation method of metal-catalyst-free CC, in which the electron donor DA was introduced into the assay system. Moreover, the enzyme-free HCR, employed as a versatile amplification way, ensures that lots of P-N can be attached to the substrate. This PEC sensing for miRNA-141 detection illustrated the outstanding linear response to a concentration variation from 0.1 fM to 0.5 nM and a detection limit down to 27 aM, without additional electron donors. The sensor is further employed to monitor miRNA-141 from prostate carcinoma cell (22Rv1), showing good quantitative detection capability. This strategy exquisitely influences the analytical performance and offers a new PEC route to highly selective and sensitive detection of biological molecules.

Carbon framework wrapped cobalt phosphide on carbon cloth (Co2P@C/CC) was synthesized via one-step CVD as a flexible electrocatalyst for the HER.

Since the oxygen evolution catalysis process is vital yet arduous in the energy conversion and storage devices, it is highly desirous but extremely challenging to engineer earthabundant, noble-metal-free nanomaterials with superior electrocatalytic activity toward effective oxygen evolution reaction (OER). Herein, we construct a prism-like cobalt-iron layered double hydroxide (Co-Fe LDH) with a Co/Fe ratio of 3:1 utilizing a facile self-templated strategy. Instead of carbon species-coupled treatment, we focus on ameliorating the intrinsic properties of LDHs as an OER electrocatalyst accompanied with hierarchical nanoflake shell, well-defined interior cavity and numerous microporous defects. In contrary to conventional LDHs synthesized via a one-pot method, Co-Fe LDHs fabricated in this work possess a huge specific surface area up to 294.1 m 2 g-1 that not only provide abundant active sites, but also expedite the kinetics of

MicroRNA (miRNAs) quantification, especially at low abundance, is vital for disease diagnosis, prognosis, and therapy. Herein we develop a distinctive label-free "off-on" configuration for photoelectrochemical (PEC) sensing platform fabrication, coupled with DNA four-way junction (4J) architecture as well as G-wire superstructure for signal amplification. In addition, ultrathin copper phosphate nanosheets (CuPi NSs) coating Au nanoparticles (Au-CuPi NSs) serve as a highly efficient photocathode substrate. To improve the sensitivity, and avoid the false positive signals, the quencher, gold nanoparticles (GNPs), is utilized to switch off the PEC signal because of the commendable surface plasmon resonance (SPR) absorption. Subsequently, ingenious DNA 4J architecture is applied to export proportional c-myc regions for target quantification. Assisted with the G-wire superstructure formation, the enhancer 5,10,15,20-tetra(4-sulfophenyl)-21H,23H-porphyrin (TSPP) is coupled on the substrate to switch on the PEC signal, thus realizing the miRNA assay with persuasive accuracy, high sensitivity, and low detection limit. In addition, we execute the miRNA detection in prostate carcinoma cell line 22Rv1, and acquire desirable quantitative capability. Remarkably, the prepared PEC sensing platform not only realizes the highly efficient miRNAs quantification, but also uncovers a marvelous horizon for sensing platform fabrication.

Herein, we focus on preparing a highly efficient photocatalytic material to construct a signal-on photoelectrochemical (PEC) sensing platform in view of the rigorous demand of accurate miRNA quantification. The well-dispersed Pt nanoclusters-coated copper phosphate ultrathin nanosheets (PtNCs/Cu(PO)NSs) were first successfully synthesized as a photoelectrode material. Because of the ultrathin two-dimensional lamellar structure of Cu(PO)NSs with a 1.3 nm thickness, as well as the homogeneous size and abundant PtNCs loaded on Cu(PO)NSs, the resultant PtNCs/Cu(PO)NSs were employed as a photoelectrode material for the first time and revealed outstanding photocatalytic activity in PEC sensing as a substrate. As a well-designed protocol, we realized accurate miRNA quantification via a novel signal amplification strategy based on G-wire superstructure exponentially ligating a signal probe, which possesses efficient and simple operation compared to the traditional amplification method. Moreover, the electron donor is generated in situ by lactate oxidase (Lox) labels catalyzing lactate for HO production, boosting the efficient separation of electron-hole pairs for further signal amplification. Impressively, this PEC sensing platform is commendably utilized to determine miRNA-141 from prostate carcinoma cell line 22Rv1. This study, considering the excellent PtNCs/Cu(PO)NSs combined with G-wire superstructure for exponential signal amplification strategy, paves a new path in biosensing and clinical diagnosis.

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