MENG, AND MILTON ELKIN. Validation of use of xenon 133 to measure intrarenal distribution of blood flow. Am. J. Physiol. 219(Z) : 440-444. 1970.-The gamma camera has been used to evaluate the distribution of radioxenon in man after injection into the renal artery. Combined gas-washout curves performed according to the method of Thorburn and associates and gamma-camera studies confirm the relationship between the first component of the gas-washout curve and clearing of radioactivity from the renal cortex. The mean cortical renal blood flow in patients with no known renal disease on a normal diet was 413 ml/min per 100 g of kidney =t 27 (SE). This represented 76.4% =t 2.7 of the total renal blood flow. The method was found to be reproducible and safe. These studies suggest that the xenon washout study is a reliable method for the determination of the intrarenal distribution of blood flow in man.
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