This paper presents a novel VLSI implementation of a MIMO detector for OFDM systems. The proposed architecture is able to perform both linear MMSE and reduced latticeaided MIMO detection, making it possible to adjust the balance between performance and power consumption. In order to facilitate real-time detection in reduced lattice mode of operation, a novel fixed-complexity version of the LLL lattice reduction algorithm has been developed, allowing for strict practical timing requirements, such as those specified for new generation IEEE 802.11n wireless LAN systems, to be met. An implementation of the MIMO detector for a system employing up to 4 transmit and receive antennas is described and its complexity and performance are evaluated.
Automated data pre-processing (DPP) forms the basis of any liquid chromatography-high resolution mass spec-trometry-driven non-targeted metabolomics experiment. However, current strategies for quality control of this im-portant step have rarely been investigated or even discussed. We exemplified how reliable benchmark peak lists could be generated for eleven publicly available datasets acquired across different instrumental platforms. Moreover, we demonstrated how these benchmarks can be utilized to derive performance metrics for DPP and tested whether these metrics can be generalized for entire datasets. Relying on this principle, we cross-validated different strategies for quality assurance of DPP, including manual parameter adjustment, variance of replicate injection-based metrics, unsupervised clustering performance, automated parameter optimization, and deep learning-based classification of chromatographic peaks. Overall, we want to highlight the importance of assessing DPP performance on a regular basis.
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