Gene regulatory networks elucidated from strategic, genome-wide experimental data can aid in the discovery of novel gene function information and expression regulation events from observation of transcriptional regulation among genes of known and unknown biological function. To create a reliable and comprehensive data set for the elucidation of transcription regulation networks, we conducted systematic genome-wide disruption expression experiments of yeast on 118 genes with known involvement in transcription regulation. We report several novel regulatory relationships between known transcription factors and other genes with previously unknown biological function discovered with this expression library. Here we report the downstream regulatory subnetworks for UME6 and MET28. The elucidated network topology among these genes demonstrates MET28's role as a nodal point between genes involved in cell division and those involved in DNA repair mechanisms.
: Water contamination 血 drainage Clitches due to soii puddling has been identified as a 皿 」 皿 portant problem a皿 d this stUdy investigated the fiitration of the resulting tuエbid waters . Bamboo coal was used as a filte 血 g material by absorbing the soil particles and other suspended materials from the tUrbid waters . In this research , effectiveness of different arrangement of barn [ boo coal in a modeled charmel was investigated . It was found out that tUrbid water filtration us 血 g 血 e net , commonly used for mandarin orange bags, was the most effective 皿 ethod . It is most probably because both the bamboo coal and the net adsorb the soil particles and the spaces betWeen them beeome se − dimentation traps. The arrangement of the bamboo coal hl the drainage area to allow space fbr sedimentation was also fbund important . K 砂 脚 rds ' 伽 r 鋸 } vaterspuriJficati ・ n ;Bam ゐ・ … al ∫ Filtering material Japan Rainwater Catohment Systems Assooiation ( JRCSA }
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