scleromyxedema is a distinct, rare entity, designated as a primary cutaneous mucinosis in the absence of endocrine dysfunction. The origin of this disorder is unknown. It is characterized by generalized papules and plaques that cause extensive thickening and hardening of the skin. Histologic changes in the dermis include proliferation of fibroblasts and excessive deposition of hyaluronic acid. In many cases there is a serum monoclonal paraprotein. Although some patients have no visceral complications, it is often a systemic disease, Involvement of a variety of internal organs has been identified.'.2 We report this as the first documented case of laryngeal involvement in scleromyxedema.
CASE REPORTA 28-year-old man was admitted to the hospital because of fever, sore throat, cough, and dysphagia.For the previous 3 years his skin had become thick and hard. The skin involvement was predominantly of the face, neck, arms, hands, chest, and back. For the last year, he had pain in his fingers and ulcerations over his knuckles. For the last 3 weeks, he reported experiencing sore throat, hoarseness, and difficulty swallowing; in the last week, liquids regurgitated through his nose and cough and fever up to 40" C developed.
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