This paper describes an instrument designed to distinguish frozen from thawed land surfaces from an Earth satellite by bouncing signals back to Earth from deployable mesh antennas.

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Human leukocyte antigen B (HLA‐B) is responsible for presenting peptides to immune cells and plays a critical role in normal immune recognition of pathogens. A variant allele, HLA‐B*57:01, is associated with increased risk of a hypersensitivity reaction to the anti‐HIV drug abacavir. In the absence of genetic prescreening, hypersensitivity affects ~6% of patients and can be life‐threatening with repeated dosing. We provide recommendations (updated periodically at http://www.pharmkgb.org) for the use of abacavir based on HLA‐B genotype. Clinical Pharmacology & Therapeutics (2012); 91 4, 734–738. doi:

ACTRN12611000492954.

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Treatment with E5 antiendotoxin antibody appears safe. It reduces mortality and enhances the resolution of organ failure among patients with gram-negative sepsis who are not in shock when treated.

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