Abstract. This study was performed to elucidate the effects of anion in the rats with adjuvant-induced arthritis. Rats were divided four groups: control (group I, n=10), arthritis (group II, n=10), arthritis with non-operation of anion generator (group III, n=10) and arthritis with operation of anion generator (group IV, n=10). Serum IL-6 and TNF-α levels were measured and histological findings of knee joints were observed in all groups. The IL-6 and TNF-α levels in group III and IV were significantly lower than those of group II. The IL-6 and TNF-α levels in group IV were significantly lower than those of group III. The inflammatory and damage degrees on the knee joints were lower in group III and IV than in group II. The degree of joint injury in group IV was less than that of group III. We first revealed that anions made by anion-generator may attenuate inflammatory and damaging effects of the arthritis. However, further study should be performed in human.
This study was designed to examine effects of Korean Berchemia berchemiaefolia (Makino) Koidz (BBK) on diet induced-fatty liver. 45 male SD rats were divided into three groups: normal diet (control group, n=15), 40% fat diet-induced obese rats (fat group, n=15), and BBK extract diet with 40% fat diet-induced obese rats (BBK group, n=15). Hematological and biochemical variables were measured. Total
This study was conducted to reveal medicinal effect of Berchemia berchemiaefolia (BB) extract for induced IBS-rat model. IBS was induced by injecting acetic acid into target of Spraque-Dawley rats' colon. Control group and experimental group were categorized as follows; Group I: control group (n=5), Group II: induced IBS (n=5), Group III: induced IBS+BB LD3 extract oral administration (n=5), Group Ⅳ: induced IBS+BB LD10 extract oral administration (n=5). The measurement of AWR was performed to determine the presence of disease leading and its alleviation. Also, we analyzed hematological factors, liver functional test, inflammatory factors, stress related factors, western blot and investigated significant differences in the variables among four groups. This research result shows that feeding orally BB extract to induced IBS rat alleviates violent contraction of colon of those rats.
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