Effects of Anion in the Rat with Adjuvant-induced Arthritis

Abstract

Abstract. This study was performed to elucidate the effects of anion in the rats with adjuvant-induced arthritis. Rats were divided four groups: control (group I, n=10), arthritis (group II, n=10), arthritis with non-operation of anion generator (group III, n=10) and arthritis with operation of anion generator (group IV, n=10). Serum IL-6 and TNF-α levels were measured and histological findings of knee joints were observed in all groups. The IL-6 and TNF-α levels in group III and IV were significantly lower than those of group II. The IL-6 and TNF-α levels in group IV were significantly lower than those of group III. The inflammatory and damage degrees on the knee joints were lower in group III and IV than in group II. The degree of joint injury in group IV was less than that of group III. We first revealed that anions made by anion-generator may attenuate inflammatory and damaging effects of the arthritis. However, further study should be performed in human.

A Study Towards Post Hoc Forensic Analysis Using Big Data Analytics

“…This works well even when there is no good training dataset where known fraudulent and nonfraudulent observations are clearly identified. Using Big Data techniques, to analyze and even predict, security incidents [13] are successful.…”

“…Therefore, most of them are focusing on gathering the network packets. There is a network forensics system, Cyber Black box, which is focused on the traffic analysis [13]. Recently, several machine learning techniques have been proposed to automate and develop intelligent network forensics systems.…”

Mudanças climáticas e envelhecimento populacional

“…Diversos estudos compreendem a população idosa como vulnerável às mudanças climáticas, ao relacionar seus efeitos ao aumento do risco de mortalidade ou prejuízos biológicos e sociais nessa faixa etária (Choi;Bae;Lim, 2017). As altas temperaturas, potencializadas pelas mudanças climáticas, afetam especialmente pessoas com mais de 85 anos, já que a capacidade termorreguladora vai se perdendo com a passagem do tempo, dificultando a adaptação a mudanças bruscas de temperatura (Huang et al, 2015).…”

“…Essa parcela da população também possui maior probabilidade de desenvolver doenças crônicas ou tomar medicamentos que prejudiquem suas funções corporais (Kenney;Munce, 2003;Hajat et al, 2010apud Cheng et al, 2018 e, além dos aspectos biológicos, pode-se apontar a maior suscetibilidade desse grupo a condições de vida mais frágeis ou exposição a ambientes sociais menos favorecidos (Choi;Bae;Lim, 2017). Schifano et al (2012) destacam as evidências de que as menores temperaturas durante o verão estão relacionadas à redução de mortalidade da população com mais de 65 anos.…”