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Aim: To determine prevalence of T 2 DM and risk factors among rural farmers of Panyam in Plateau Central, Nigeria. Background: Diabetes mellitus is one of the commonest metabolic disorder characterized by persistent hyperglycemia due to lack of insulin secretion or inactivity of insulin resulting in risk of microangiopathy and macroangiopathy [1,2]. Many lifestyle factors affect the incidence of Type II Diabetes Mellitus, which includes cigarette smoking, inactivity and heavy alcohol consumption that could cause hyperuriceamia. Other risk factors include obesity, age, family history. Materials and Methods:The study population consisted of 200 adults above 40 years mainly farmers. Both females and males were recruited into the study.

Background: In developing countries like Nigeria, with poor socioeconomic , early marriage, poor acceptance of contraception, poor spacing of pregnancies, high fertility rate and poor maternal and child health indices, leading to poor maternal-child outcome. There is a need to investigate the pattern of serum lipid changes during pregnancy in Nigeria women as hyperlipidemia may lead to poor maternal outcome. Materials and methods: A total of one hundred and forty (140) subjects between the ages of 20 and 45 years with mean age 29.74 ± 6.5 years of the study population. Group 1: the control comprises of thirty-five (35) healthy non pregnant subjects with mean age of 26.84 ± 5.2 volunteers of Nigeria origin. Group 2: the test involved one hundred and five (105) apparently healthy pregnant Nigerian women subdivided into three groups; X, Y and Z each made of thirty-five (35) subjects distributed into 1 st , 2 nd and 3 rd trimester of pregnancy respectively. The TG assay was analyzed using enzymatic spectrophotometric method as described by Biosystems. Results: The result analysis showed a significant increase (p ≤ 0.05) in the TG level during the first trimester of pregnancy when compared with control as shown in Table 1. There was a significant increase (p ≤ 0.05) in the TG levels during the second trimester of pregnancy when compared with that of the control subjects. During the third trimester of pregnancy there was a significant increase in TG levels when compared with the control subjects. Conclusion: This work revealed that the most dramatic change in the lipid profile in normal pregnancy is serum hypertriglyceridemia, which may be as high as two-three folds in the third trimester over the levels in non pregnant subjects. The estimation of lipid profile is strongly recommended as part of the laboratory investigations during pregnancy.