In this paper, two structure-preserving nonstandard finite difference (NSFD) operator splitting schemes are designed for the solution of reaction diffusion epidemic models. The proposed schemes preserve all the essential properties possessed by the continuous systems. These schemes are applied on a diffusive SEIQV epidemic model with a saturated incidence rate to validate the results. Furthermore, the stability of the continuous system is proved, and the bifurcation value is evaluated. A comparison is also made with the existing operator splitting numerical scheme. Simulations are also performed for numerical experiments.

Objective: To determine the reference values of normal portal vein diameter in correlation to gender in population of Lahore. Study Design: Cross Sectional study. Setting: Ultrasound Lab University of Lahore and Gondal Complex Lahore. Period: 5th October 2020 to 13th April 2021. Material & Methods: Sample size of my study were 164 males and 143 females. Simple random sampling was conducted. Healthy Individual with normal body mass index, both (male and female) individuals in fasting state and age between (20-25) years. Individual with history of portal hypertension, Fatty liver, Hepatomegaly and any other hepatic disorder. Xario XG. Convex 3.5 MHz-7.5MHz. Results: The mean diameter of portal vein for male was calculated as 10.51 + 1.468 mm (ranging from 13mm to 15mm), and for females was 10.085 ±1.336 mm (ranging from 7 to 14mm). Independent t-test was applied to examine the difference of mean Portal vein in males and females. We found a statistical significant difference in two means of portal vein diameter as the p-value = 0.008 is less than α =0.05. Conclusion: In this study, portal vein diameter in adult men and women were found within the normal range among age limit 20-25years.But the diameter of portal vein showed direct relation with weight and Body Mass Index among females but in males none of the body factors had any impact on the diameter of portal vein.

Background: The purpose of the study is to evaluate and compare the changes associated with hepatosteatosis in diabetic obese versus diabetic normal-weight patients through ultrasonography. It is estimated that with the prevalence of about 30%–75% of obese individuals accordingto the body mass index (BMI) criteria are at increase risk of developing simple fatty live. Besides obesity, diabetes mellitus is also considered to be one of the important causes of hepatosteatosis. Methods: This prospective study was conducted in February 2015–December 2015 on a group of 181 diabetic patients, including 65 males and 116 females with an age range of 40–80 years. The patients were divided into two diabetic groups: those having a BMI ≥30 kg/m 2 were included in the obese group ( n = 116) and those with a BMI of 18.5–25 kg/m 2 were included in the normal BMI group ( n = 65). Ultrasound machine Esaote MyLab 50 equipped with a 3.5–5 MHz curvilinear multifrequency transducer was used to scan the liver. Independent samples t -test was performed to compare the liver span in the two groups. Chi-square tests were applied to compare the frequencies of fatty changes, border, and surface characteristics. Results: The presence of fatty changes among obese groups was statistically significant in the diabetic obese group compared to the normal-weight individuals with P < 0.0001. Similarly, hepatic spans were found to be significantly greater in the diabetic obese group than the diabetic normal BMI group on independent samples t -test with P < 0.0001. Females were seen to develop hepatosteatosis more frequently compared to males in all diabetic individuals with P = 0.02. Conclusion: It is concluded that diabetic obese patients are more prone to develop hepatosteatosis as compared to normal BMI diabetic individuals.

Prediction of gestational age based on sonographic fetal parameters is perhaps the cornerstone in modern obstetrics. The transverse cerebellar diameter serves as a reliable predictor of GA in the fetus and is a standard against which abnormalities in other fetal parameters can be compared. A variety of sonographic fetal biometric parameters can be used to assess gestational age in the second and third trimesters of pregnancy. The TCD is an additional biometric parameter against which aberrations in other fetal parameters can be compared. Objective: To assess the predictability of GA calculated by fetal TCD measured in 2nd & 3rd trimester of pregnancy on ultrasound. Methods: This was an cross-sectional study with a sample size 371 healthy, pregnant females with a normal fetus included aged 18 to 40 years, conducted in Gilani ultrasound center ferozpur road lahore. A standard 2nd and 3rd trimester ultrasound examination was done. In addition to the standard biometric parameters, the transcerebellar diameter was also measured. The collected data was subjected to statistical analysis. Results: Pearson product-moment correlation coefficient method was applied at a significance level of 1% (α = 0.01).using statistical software SPSS version 23.0. It was observed that BPD and TCD had a statistically significant, strong, linear correlation (r=0.976), GA of FL (r=0.978), LMP (r=0.976) P value (0.000) were considered significant. Conclusion: The TCD is a reliable parameter for the determination of GA in the  2nd & 3rd  trimesters of pregnancy. Int. J. Appl. Sci. Biotechnol. Vol 6(4): 379-385

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Recently, demand for fermented foods has increased due to their improved nutritional value, taste, and health-promoting properties. Worldwide consumption of these products is increasing. Fermented foods are generally safe for human consumption. However, some toxins, primarily biogenic amines (putrescine, phenylethylamine, histamine, tyramine, and cadaverine), mycotoxins (fumonisins, aflatoxins, ochratoxin A, zearalenone, and trichothecenes), and bacterial toxins (endotoxins, enterotoxins, and emetic toxins) can be produced as a result of using an inappropriate starter culture, processing conditions, and improper storage. These toxins can cause a multitude of foodborne illnesses and can lead to cardiovascular aberration and adverse gastrointestinal symptoms. Analytical techniques are in use for the detection of toxins in fermented foods for monitoring and control purposes. These include culture, chromatographic, immunoassays, and nano sensor-based techniques. These detection techniques can be used during the production process and along the food chain. On an industrial scale, HPLC is widely used for sensitive quantification of toxins in fermented foods. Recently, biosensor and nano sensor-based techniques have gained popularity due to accuracy, time efficiency, and simultaneous detection of multiple toxins. Other strategic methods being investigated for the removal of toxins from fermented foods include the use of specific starter cultures for bio-preservation, aflatoxin-binding, and biogenic amine-degradation agents that may help to appropriately manage the food safety concerns associated with fermented foods.

Objectives: To determine sonographic association of uterine fibroids with infertility among women of childbearing age. Study Design: Cross-sectional study. Setting: Gilani Ultrasound Clinic opposite Lahore General Hospital, University of Lahore. Ahsan Diagnostic Centre, Sialkot. Period: From 10th July to 10th October 2018. Materials & Methods: The study was started after the approval of ethical committee of the University of Lahore. All the patients were enrolled in this study after signing the informed consent form. Toshiba Xario and Medison Accuvix V20 with convex transducer frequency ranging from 2 to 6 MHz were used. Fibroids were evaluated through trans-abdominal scan and sonographic data was stored in the ultrasound machine. A convenient sampling technique was used and data was further analyzed with the help of Statistical Package for the Social Sciences version 24 (SPSS 24, IBM, Armonk, NY, United States of America). Results: Among 113 subjects, the incidence of uterine fibroid was 32.7%. A significant association (p-value=0.010) was seen between existence of fibroid and the type of Infertility. The mean size of the fibroids was found to be 32.3568mm, 26(23.0%) of participants had single while 11(9.7%) of them had multiple fibroids. The location was most commonly seen in anterior and posterior wall, whereas the most common type was found to Sub-Mucosal and Sub-Serosal. Conclusion: Uterine Fibroids were commonly associated with Secondary infertility as compared to primary infertility.

Background:The purpose of the research is to know the sonographic evaluation of urolithiasis formation with positive family history in population of Lahore because urolithiasis is a major problem in Pakistan. According to a survey in 1985–1987 the incidence rate reaches to 8.3/100,000 individuals in the Punjab. In Pakistan, urolithiasis is the sixth major cause of surgery. The study was conducted to rule out the role of positive family history in people suffering from urolithiasis.Materials and Methods:This was an observational cross-sectional study conducted at the Radiology department of the University of Lahore teaching hospital and Gilani Ultrasound center-Afro-Asian Institute, Lahore, Pakistan. A total of 125 patients were included in the study which were diagnosed with urolithiasis and individuals with any other abnormality were excluded from the study. The duration of the study was from January 2017 to April 2017. Data were tabulated and analyzed using SPSS version 24. The data were reported using descriptive and inferential statistics. The quantitative variable like age was assessed using mean standard deviation and standard errors. The qualitative variables like gender were reported using percentages and frequencies.Results:Urolithiasis is commonly seen in the males (77 individuals out of 125) as compared to females (48 individuals out of 125) and mid pole of right kidney is the most common site of the renal stones deposition (13.6%), and the relationship of father is mostly seen as familial history (39.2%).Conclusion:It is concluded that positive family history is the major predisposing factor in urolithiasis and one of the cause in the development of stones in the urinary tract or in other words people who have a history of urolithiasis in blood relations have more tendency of stone formation in any part of their lives. Its positive aspect is that we can do a screening in blood relations, especially whose parents or family members diagnosed with stones and can do preventive measures for that. Moreover, its negative aspect is that there are several causes of the stone formation in the urinary tract.