The aim of this review was to investigate usage of computer-aided design/computer-aided manufacture (CAD/CAM) such as milling and rapid prototyping (RP) technologies for removable denture fabrication. An electronic search was conducted in the PubMed/MEDLINE, ScienceDirect, Google Scholar, and Web of Science databases. Databases were searched from 1987 to 2014. The search was performed using a variety of keywords including CAD/CAM, complete/partial dentures, RP, rapid manufacturing, digitally designed, milled, computerized, and machined. The identified developments (in chronological order), techniques, advantages, and disadvantages of CAD/CAM and RP for removable denture fabrication are summarized. Using a variety of keywords and aiming to find the topic, 78 publications were initially searched. For the main topic, the abstract of these 78 articles were scanned, and 52 publications were selected for reading in detail. Full-text of these articles was gained and searched in detail. Totally, 40 articles that discussed the techniques, advantages, and disadvantages of CAD/CAM and RP for removable denture fabrication and the articles were incorporated in this review. Totally, 16 of the papers summarized in the table. Following review of all relevant publications, it can be concluded that current innovations and technological developments of CAD/CAM and RP allow the digitally planning and manufacturing of removable dentures from start to finish. As a result according to the literature review CAD/CAM techniques and supportive maxillomandibular relationship transfer devices are growing fast. In the close future, fabricating removable dentures will become medical informatics instead of needing a technical staff and procedures. However the methods have several limitations for now.

Two techological approaches for fabricating dentures; computer-aided design and computer-aided manufacturing (CAD/CAM) and rapid prototyping (RP), are combined with the conventional techniques of impression and jaw relation recording to determine their feasibility and applicability. Maxillary and mandibular edentulous jaw models were produced using silicone molds. After obtaining a gypsum working model, acrylic bases were crafted, and occlusal rims for each model were fabricated with previously determined standard vertical and centric relationships. The maxillary and mandibular relationships were recorded with guides. The occlusal rims were then scanned with a digital scanner. The alignment of the maxillary and mandibular teeth was verified. The teeth in each arch were fabricated in one piece, or set, either by CAM or RP. Conventional waxing and flasking was then performed for both methods. These techniques obviate a practitioner's need for technicians during design and provide the patient with an opportunity to participate in esthetic design with the dentist. In addition, CAD/CAM and RP reduce chair time; however, the materials and techniques need further improvements. Both CAD/CAM and RP techniques seem promising for reducing chair time and allowing the patient to participate in esthetics design. Furthermore, the one-set aligned artificial tooth design may increase the acrylic's durability.

Co-Cr metal posts fabricated by CCM and DMLS could be an alternative to TC processing in daily clinical application.

Objectives:The aim of the present study was to evaluate the cytotoxic effects of three different provisional restoration materials on fibroblasts. Two bis-acrylic based [Tempofit Duomix (Detax), Protemp 3 Garant (3M ESPE)] and one urethan dimethacrylate [Revotek LC (GC Corporation)] based provisional restoration materials used.Methods:Materials were prepared according to the manufacturers’ instructions in standard teflon disks (2×5 mm) and four samples were extracted in 7 ml of Basal Medium Eagle with 10% new born calf serum and 100 mg/ml penicillin/streptomycin for 24 hours. The L929 fibroblast cells were plated (25.000 cells/ml) in well plates, and maintained in a CO2 incubator at 37°C for 24h. After 24 hours, the incubation medium was replaced by the immersed medium in which the samples were stored and the L929 fibroblasts were incubated in contact with eluates for 24 hours at 37°C for 24h. The fibroblast cell viability was analyzed by measuring the mitochondrial activity with the methyltetrazolium test (MTT). Twelve well used for each specimen and experiment repeated for two times. The data was statistically analyzed by Mann-Whitney U tests.Results:The results showed that, Revotek LC and Protemp 3 Garant were not cytotoxic for fibroblast cells when compared to control group (P>.05). However, Tempofit duomix was cytotoxic for L929 fibroblasts when compared to control group and other tested materials (P<.05).Conclusions:Taking into consideration the limitations of an in vitro study, our study indicate that provisional restoration materials might have cytotoxic effects on fibroblasts and should be selected carefully for clinical applications.

Background/purpose: The aim of this study was to determine the accuracy of casts made from irreversible hydrocolloid impressions with immediate and delayed pouring. Materials and methods: A master model was mounted on a modified articulator designed to standardize impression procedures. A total of 250 impressions were taken and grouped into 25 groups (n Z 10) according to irreversible hydrocolloid material (CA37, Tropicalgin, ColorChange, Hydrogum 5, and Hydrocolor 5) and storage time (0 hours, 1 hour, 24 hours, 72 hours, and 120 hours). Impressions were stored at 23 AE 1 C and 100% relative humidity and poured with gypsum at the predetermined storage time. Casts were scanned with a threedimensional (3D) model scanner. The digital models were measured and subtracted from the measurements obtained from the master model. The absolute values of dimensional differences were statistically analyzed using two-way analysis of variance (ANOVA) and post hoc Fisher LSD test (P < 0.05). Results: Different irreversible hydrocolloids and pouring times showed significant differences (P < 0.001). In all irreversible hydrocolloids, no statistically significant differences were found with impressions poured after 0 hours, 1 hour, and 24 hours of storage (P > 0.05). However, after 72 hours and 120 hours of storage, Tropicalgin and CA37 irreversible hydrocolloid impressions were found to be significantly different (P < 0.05). Moreover, ColorChange, Hydrogum 5, and Hydrocolor 5 irreversible hydrocolloid impressions were not statistically different up to 120 hours (P > 0.05). (M. Dinçel). + MODELPlease cite this article in press as: Gümüs ‚ HÖ, et al., The effect of pouring time on the dimensional stability of casts made from conventional and extended-pour irreversible hydrocolloids by 3D modelling, Journal of Dental Sciences (2014), http://dx.