Citation of This Article AbstractThis study was conducted to assess the effects of different doses of butaphosphan-cyanocobalamin combination onbody condition score (BCS), betahydroxybutyrate (BHBA) and reproductive parameters in cows with subclinical ketosis (SCK). Holstein-Friesen cows (n=544) were checked for BHBA concentration. Cows with SCK (n=53, BHBA ranging from 1.00 to 3.00 mmol/L) were assigned randomly to receive saline (C0, n=18), 5 mL/100 kg BW (C5, n=18) or 10 mL/100 kg BW (C10, n=17) butaphosphan-cyanocobalamin combination. BHBA concentration was measured on d 0, 10, and 18 relative to treatment application. BCS was evaluated weekly until d 60 postpartum. For reproductive parameters cows were monitored until d 150 postpartum. The median reduction in blood BHBA concentrations was 28, 57, and 75% for C0, C5, and C10, respectively. NEFA and total bilirubin concentrations were significantly decreased in C10 group. The relative median change in BCS as compared to baseline was 17, 12, and 6% for C0, C5, and C10, respectively. Between d 15 and 25 postpartum uterine involution was completed in 44, 83, and 88% of cows in groups C0, C5, and C10, respectively. Interval from calving to first insemination in group C10 was shorter than control group. Overall pregnancy rate was not different among groups. In conclusion butaphosphan-cyanocobalamin combination decreased severity of hyperketonemia, stimulated uterine involution, shortened time to first insemination and increased pregnancy rate. Keywords: Beta hydroxybutyrate, Butaphosphan, Cyanocobalamin, Subclinical ketosis, Reproductive performance Subklinik Ketosisli Süt İneklerinde Farklı Dozlarda Butafosfan ve Siyanokobalamin Kombinasyonunun Etkisinin Değerlendirilmesi ÖzetBu çalışma, subklinik ketozisli (SCK) süt ineklerinde farklı dozlarda butafosfan-siyanokobalamin kombinasyonunun vücut kondisyon skoru (VKS), betahidroksibütirat (BHBA) ve reprodüktif parametreler üzerine etkilerini değerlendirmek amacıyla gerçekleştirildi. Holştayn-Frizyan inekler (n=544) BHBA yönünden kontrol edildi. SCK'li inekler (n=53, 1.00-3.00 mmol/L BHBA); 4 gün süresince günlük salin uygulanan (C0, n=18) ve canlı ağırlığa 5 mL/100 kg dozunda (C5, n=18) ya da canlı ağırlığa 10 mL/100 kg dozunda (C10, n=17) butafosfan-siyanokobalamin kombinasyonunun uygulandığı gruplara rastgele olarak ayrıldı. BHBA düzeyleri; 0, 10 ve 18. günlerde ölçüldü. VKS postpartum 60. güne kadar haftalık değerlendirildi. Reprodüktif parametreler için inekler doğum sonrası 150. güne kadar takip edildi. Kan BHBA düzeyinde medyan azalma C0, C5 ve C10 grubunda sırasıyla %28, %57 ve %75 olarak gerçekleşti. NEFA ve total bilirübin düzeyleri C10 grubunda anlamlı şekilde azaldı. VKS'un relatif medyan değişimi baseline ile karşılaştırıldığında C0, C5 ve C10 grubunda sırasıyla %17, %12 ve %6 olarak belirlendi. Postpartum 15 ve 25. günler arasında uterus involüsyonu C0, C5 ve C10 gruplarında sırasıyla %44, %83 ve %88 tamamlandı. C10 grubunda buzağılama ilk tohumlama aralığı kontrol grubundan daha kısaydı. Ortalama gebeli...
Özet: On bir yaşlı, erkek yerli bir kedideki unilateral hidronefrozis olgusu tanımlandı. Klinik incelemede dehidrasyon, koordinasyon bozukluğu, k:aslarda zayıflık, titreme, derin solunum ve abdominal palpasyonda duyarlılık tespit edildi. Vücut ısısı dü-şüktü. Serum üre nitrojen değeri 337 mg/dı, keratinin 15,2 mg/dı olarak belirlendi. Ortalama eritrosit hacmi (mean corpuscular volume=MCV) ve hematokrit (packed cell volume=PCV) değerlerinde artış kaydedildi. Abdominal ultrasonografi sonucunda sol böbrekte pelvis renalisin genişlemiş olduğu görüldü. Nekropside ve histopatolojik incelemede sol üreterde göze çarpıcı stenotik lumen ve mukozada fibrozis gözlendi. Sol böbrekte kronik glomerulonefritis dikkati çekti. Sağ böbrek ve üreterde herhangi bir değişikliğe rastlanmadı.Anahtar kelimeler: Hidronefrozis, kedi, üriner yetmezlik Unilateral hydronephrosis in a catSummary: In this study, unilateral hydronephrosis was described in a 11 year-old domestic male caL. Dehydration, trembling, incoordination, and weakness of the muscle were observed clinically. Hypersensitivity to abdominal palpation and deep respiration were another clinical findings. Body temperature was low. An examination of the blood serum urea nitrogen and creatine were 337 mg/dj, 15,2 mg/dı, respectively. High values for MCV (65 ll), PCV (52%) were found in the serum biochemical analysis. Hydronephrosis of left the kidney was seen at the abdominal ultrasonography. Marked stenotic lumen and massive fibrosis of the mucosa in the left ureter were observed. In the left kidney, chronic glomerulonephritis was detected. The right kidney and ureter were normal in appearance at necropsy and histological examination.Key words: Cat, hydronephrosis, urinary incompetence GirişBir çok hayvanda üriner yetmezlik ve hidronefrozis tanımlanmıştır (l ,7,8). Kedide ise üriner yetmezlik kö-peklerden çok daha az olarak bildirilmiştir (2). Buna karşılık, ektopik üreterin en yaygın komplikasyonu kedilerde hidroüreter/hidronefrozis olarak saptanmıştır (3,5).Kedide hidronefrozise az rastlanması bu sunumun amacını oluşturmuştur. Materyal ve MetotÇalışmanın materyalini Ankara Üniversitesi, Ve- Bulgular Klinik bulgularKliniğe agoni halinde getirilen kedinin beden ısısı 37,5°C idi. Aynca kusma, dehidrasyon, deri elastikiyetinde azalma, koordinasyon bozukluğu, kaslarda zayıflık, titreme, derin solunum, abdominal palpasyonda duyarlılık ve sol böbrekte büyüme tespit edildi. Abdominal ultrasonografi sonucunda sol böbrekte pelvis renalisin genişlemiş olduğu gözlendi (ŞekilI).
Pulmonary veno-occlusive disease (PVOD) is an uncommon disease in humans and animals caused by pulmonary hypertension (PH). The aim of this study was to investigate pathomorphological findings of PVOD in a cat. A mass was detected in the right atrium with echocardiography in an 11-year-old male cat. Following treatments, necropsy of the cat was performed after death due to respiratory failure. Macroscopically, masses were detected in mesenteric lymph node, mediastinal lymph node and, heart. Congestion and consolidated areas with edema were seen in the examination of the lung. Histopathologically, neoplastic lymphoid cells were observed in intestine, lymph nodes and heart. In lung, vein lumens were almost completely occluded by mostly loose intimal fibrosis. Near affected veins, increasing in number of the capillaries was observed. While intimal fibrosis was detected by Masson's trichrome staining, the occluded veins were demonstrated by Verhoeff-van Gieson staining. In this case report, pathomorphological evaluation of PVOD was performed and as a result of clinicopathological examinations; PVOD, intestinal lymphoma, and cardiac metastasis were described in a male cat.
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