In 2019, the EPMA celebrated its 10th anniversary at the 5th World Congress in Pilsen, Czech Republic. The history of the International Professional Network dedicated to Predictive, Preventive and Personalised Medicine (PPPM / 3PM) is rich in achievements. Facing the coronavirus COVID-19 pandemic it is getting evident globally that the predictive approach, targeted prevention and personalisation of medical services is the optimal paradigm in healthcare demonstrating the high potential to save lives and to benefit the society as a whole. The EPMA World Congress Supplement 2020 highlights advances in 3P medicine.
The prevalence of sharp respiratory diseases is very wide. The disease affects all age groups of the population. It is known that every adult man per year is sick of a sharp respiratory disease from 2 to 4 times. This forms a greater danger of complications in the lungs-free and creates a large number of cases of disability, and therefore gives material damage. The effect on the organism of the causative agent of acute respiratory viral infection can vary significantly depending on the etiology, age of the patient, the state of his immune system, and the presence of concomitant diseases. Against the background of the height of the disease, symptoms of intoxication prevail chills, a sharp headache with overwhelming localization in the frontal region and temples, pain in the muscles and joints, pain when the eyeballs move or when pressure is applied to them, lacrimation, severe weakness, and fatigue. With acute respiratory disease, intoxication, hemorrhagic and respiratory syndromes are developing. The relative benignness and short-term flow of this disease leads to the fact that the majority of patients do not seek medical attention. For this reason, it is far from always possible to diagnose the species affiliation of the pathogen.
Social integration and comprehensive rehabilitation of people with disabilities with cerebral palsy occupies one of the leading places in physical rehabilitation. In all corners of the globe, medical workers and specialists of therapeutic physical culture constantly use the means of hippotherapy (Equine-assisted therapy) as a rehabilitation of people with cerebral palsy. The authors developed and tested the technique of hippotherapy in the process of development of motor functions and the formation of skills of household self-care in children aged 4-6 with the manifestation of a spastic form of infantile cerebral palsy. Subjects had different degrees of motor disorders; the average assessment of the degree of clinical manifestations prior to the start of the experiment was 2.2 points. The technique includes three stages of conducting exercises with the performance of exercises riding on the horse, aimed at normalizing the pathological muscle tone, the formation of the correct motor stereotype, the stimulation of tactile and proprioceptive sensitivity, the development of motor skills and the reduction of dysarthria, increasing the level of motor functions, which contributes to social rehabilitation of children with this disease. A low degree of social adaptation is due to the age of sick children and the short duration of mastering skills, as well as excessive guardianship by parents.
The properties of erythrocytes strongly determine the course of the entire microcirculation and metabolism in the body. Elucidation of the state of students who had long-term low physical fitness and began to regularly perform feasible physical exercises can track the progress of optimization of erythrocyte parameters that are significant for microcirculation. The study involved 42 male students who had low physical activity throughout their future life and who began regular athletics training 3 times a week. The control group included 46 students who, for at least 7 years, regularly experienced athletics loads at least 3 times a week. The work uses standard proven biochemical, hematological, and statistical research methods. After six months of physical training in the blood of students, previously poorly physically trained, normalization of metabolites of arachidonic acid, a decrease in the amount of cholesterol and acyl hydroperoxides in erythrocytes, and an increase in the level of phospholipids in them. During these periods, the students who started training experienced an increase in the number of erythrocytes-discocytes and a decrease in the number of all altered forms of erythrocytes. For students with low physical activity, who began regular physical training, a gradual improvement in the surface properties of erythrocytes is characteristic, which facilitated the processes of microcirculation in tissues.
Regular mental exercises are currently considered an important component of the rehabilitation of various categories of patients with organic brain disorders. The study was carried out with the help of the Russian Internet portal "Chess Planet", which makes it possible to obtain information about persons with disabilities in the course of their sports training. The study involved 28 people with cerebral palsy at the age of 19-27, out of whom 25 were at the stage of sports specialization and 3 people were at the stage of improving sports skills. The study was carried out using the testing method and the method of statistical processing. After analyzing the data obtained, we can talk about the positive influence of the process of mastering the chess game on the psychophysical status of young people with cerebral palsy. This kind of sport increased the level of their sports training, their resistance to stress and steadily improved the general psychosomatic state. Even taking into account the developing decrease in the values of the considered indicators at the control stage of the study, the subjects had an increase of 13.7% in comparison with the preliminary stage of the study.
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