A reliable and valid conversion factor of 4 cm following TN manometry permits accurate TO placement of the Bravo capsule without endoscopy. TO, unsedated Bravo placement is safe, well tolerated, and may minimize costs and potential risks associated with endoscopy.
This investigation was undertaken to define the pressure profile of the canine ileocolonic junctional segment and to determine whether a zone of increased pressure exists between the ileum and colon. In four adult dogs, the area was made accessible by bringing ileal and colonic stomas to the abdominal wall. An open-tipped, water-filled polyethylene tube and miniature balloons, 5 x 10 and 7 x 7 mm, tied over identical tubes and connected to pressure transducers were withdrawn at 0.5-cm intervals from the colon into the ileum of the fasted, conscious animals. In many instances, a zone of elevated pressure was encountered. Mean pressures at the center of the junctional area by the open-tipped tube were 19.7 (sem ± 1.43) cm H2O above ambient, 5 x 10 mm balloon 37.7 (sem ± 2.16) and 7 x 7 mm balloon 47 (sem ± 1.73). Similar pressures were recorded at this site when units were withdrawn from ileum to colon. Length of the zone was usually 1 cm. Simultaneous cinefluorographic pressure studies showed that the zone of increased pressure was located in the cone-shaped configuration indicating the ileocolonic junction.
The Bravo pH capsule is a safe, well-tolerated test to evaluate acid reflux symptoms in children, and the data obtained frequently changes patient management.
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