Gaining further insight into the issue of moral distress among nurses and the clinical situations that most frequently cause this distress will enable development of strategies to reduce moral distress and to improve nurse satisfaction and, consequently, patient care.

The majority of hospitalized older adults with polypharmacy think they are taking a lot of drugs and would like to reduce this number. Older adults should not be considered a major limitation on deprescribing interventions. Future research should examine this issue with qualitative studies in order to gain a more in-depth understanding and explore how these findings can be translated into a multidisciplinary deprescribing process.

The Conley Scale is indicated for use in the medical sector, on the strength of its high sensitivity. However, since its specificity is very low, it is deemed useful to submit individual patients giving positive results to more in-depth clinical evaluation in order to decide whether preventive measures need to be taken. In surgical sectors, the low sensitivity values given by both scales suggest that further studies are warranted.

The present study provides further insight into the moral distress experienced by nurses working in Italian NICUs.

These findings will provide indications on the strategies needed to overcome such barriers.

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The idea that mutuality is effective in nurse-patient relationships is pivotal in nursing and leads to more compassionate and egalitarian care (Brown, 2016). Mutuality, defined as a form of social cooperation based on mutual protection and assistance, is a reciprocal relationship between two or more people, groups, or institutions (Brown, 2016). In the last 30 years, a large and growing international literature on mutuality has developed (Pucciarelli et al., 2021).Mutuality in the relationship between nurses and patients has been previously defined as 'high levels of empathy, collaboration, equality and interdependence' (Jeon, 2004, p. 128). Mutuality is a process, which takes place through relationship, communication, and educational activities. Mutuality between nurse and patient can have an

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