ResumoA parvovirose é uma doença infecciosa viral, altamente contagiosa, que acomete cães causando enterite aguda. A desidratação é um problema secundário e de evolução aguda, sendo este o foco principal do tratamento. O objetivo deste estudo foi avaliar dois tratamentos de reposição volêmica em cães com diagnóstico confirmado de parvovirose por detecção do antígeno nas fezes por meio de ELISA. Foram utilizados 15 cães, mestiços, machos e fêmeas, com idade de 3 a 6 meses, destes, quatro vieram a óbito durante o tratamento e 11 foram incluídos no estudo. Os pacientes foram alocados aleatoriamente em dois grupos: Grupo Hidroxietilamido 130/0,4 (HES, n=6) e Grupo Ringer Lactato (RL, n=5), os quais receberam fluidoterapia com hidroxietilamido 130/0,4 e solução de Ringer Lactato, respectivamente, com base nos cálculos de déficit hídrico. Todos os animais receberam por via intravenosa: cefalotina, metronidazol, ranitidina e metoclopramida. Durante o internamento, a cada 12 horas foram avaliados os gases sanguíneos arteriais, eletrólitos e realizou-se exame clínico completo (frequência cardíaca, frequência respiratória, temperatura retal, tempo de preenchimento capilar, vômito, apetite, desidratação, ganho de peso, hematoquezia, melena, hematêmese e dor abdominal) e a cada 24 horas hemograma. Em comparação ao basal, no grupo RL houve aumento nos valores de PaO 2 e diminuição nos níveis de hemoglobina, hematócrito, fósforo e magnésio; e no grupo HES, ocorreu diminuição na porcentagem de desidratação, hemoglobina, fósforo e potássio. Não foram observadas diferenças significativas nos demais parâmetros entre os grupos. Ambos os tratamentos foram efetivos na reposição volêmica dos pacientes, não diferindo em nenhuma variável analisada. Palavras-chave: Parvovírus, Eletrólitos, Hidroxietilamido 130/0,4, cães AbstractParvovirus is an infectious viral disease, highly contagious, affecting dogs causing acute enteritis. Dehydration is a minor problem and acute evolution, which is the main focus of treatment. The objective of this study was to evaluate two treatments volume replacement in dogs with confirmed diagnosis of 1 Médico Veterinário Autônomo, Lages, SC.

RESUMO Os felinos são defi cientes na biotransformação do propofol e os dados em relação à farmacocinética nessa espécie 2, 5, 10, 15, 30 e 60 minutos de infusão e aos 5, 10, 15, 30, 60, 90, 120, 180, 240, 360, 600 2, 5, 10, 15, 30, and 60 minutes of infusion and at 5, 10, 15, 30, 60, 90, 120, 180, 240, 360, 600 and 1440

The present study aimed to evaluate the effects of different sedation protocols on blood pressure and echocardiographic and electrocardiographic parameters in dogs. In total, 24 male mixed-breed dogs with a mean weight of 9.87±3.0kg were used.Animals were randomly divided into four groups (n=6), which were subjected to sedation using the following protocols: acepromazine (0.05mgkg -1 ) and butorphanol (0.3mgkg -1

Proper monitoring of cardiac index (CI) in Simpson's method; 3.4±0.9, 3.1±0.7, 2.6±3.4, and 3.6±0.8, 3.6±0.8, 2.7±0.6 and 6.2±1.5

This is a case report that describes a severe condition of exungulation with distal phalanxavulsion in a mare, Quarter Horse of nine years old, attended at the Veterinary Hospital(HCV) from the Santa Catarina State University (CAV/UDESC), Lages, SC, Brazil. Theanimal showed exungulation of the right hindlimb due to transportation trauma and presentedwith severe lameness. All radiographs demonstrated osteoproliferative reaction in theproximal and middle phalanges and absence of the distal phalanx and the alar cartilage andsevere peripheral soft tissue swelling. Due to the extensive injury with severe involvement ofthe distal phalanx and poor prognosis euthanasia was recommended and performed.

We used 12 healthy red howler monkeys, weighing 6.4±0.4 kg, which were fasted and without water six and two hours, respectively. The animals were divided into two groups that received intramuscular injection: TZ (n=6) which received tiletamine-zolazepam (Zoletil ® ) at a dose of 3.6mg/kg and CEMTRA (n=6) which received ketamine S (+), tramadol and midazolan (Cemtra ® , pilot batch 001/10, Ouro Fino Saúde Animal Ltda, Cravinhos/SP, Brazil, comprising 100mg/ml of ketamine S (+), tramadol 20mg/ml and 10mg/ml of midazolam) in dose of 1ml of the association for each 10kg of body weight, equivalent doses of 10mg/kg, 1mg/kg and 2mg/kg, respectively. Prior to administration of drugs (M0) were evaluated: heart rate (HR), respiratory rate (RR), rectal temperature (RT), capillary refill time (CRT), systolic arterial pressure (SAP), hemoglobin oxygen saturation (SpO2 ), presence of salivation, degree of muscle relaxation and sedation, Bispectral index (BIS) and Signal Quality BIS (SQI), interdigital pinch response and latency times, ambulation and total recovery (TRT). The parameters were reassessed M5, M10, M20, M30, M40 and M50 (5, 10, 20, 30, 40 and 50 minutes after drug administration). In TZ animals were more responsive to the interdigital pinch over time. The animals of CEMTRA showed a higher degree of muscle relaxation and sedation. The RR of CEMTRA was lower after administration of treatment at all times in relation to M0. Among the groups RR of CEMTRA was lower compared to the TZ in M2 and M4. The total time of sedation and recovery was 48±4 min and 150.1±42.1 for the CEMTRA and 38±7 and 73.1±20.6 for the TZ. We conclude that both formulations are safe for containing chemical howler, and the CEMTRA showed better sedation and muscle relaxant.

A anestesia intravenosa é amplamente emprega em cães e a adição de adjuvantes complementa a analgesia e reduz doses de propofol empregadas. O objetivo deste estudo foi avaliar a associação da dexmedetomidina ao propofol na anestesia intravenosa em cães. Foram selecionadas 15 cadelas, adultas, hígidas, pesando 13,8 ±4,7 kg. Após pré-medicação com acepromazina e metadona, foram distribuídas nos grupos GDEX (n = 8) em que foi administrada dexmedetomidina (2 µg/kg em bolus + 1 µg/kg/h IV) ou controle GC (n = 7), com salina no mesmo volume, para então administrar propofol em ambos grupos. Os animais foram mantidos com propofol ajustando-se a taxa ao plano anestésico e suplementados com oxigênio à 100%. Foram avaliados: escala de indução, eletrocardiograma, frequências cardíaca e respiratória, pressão arterial sistólica com doppler, pressão de gás carbônico expirado e saturação de oxigênio periférico. Quando necessário foi administrado fentanil (2,5 µg/kg IV). Ao final, foram contabilizados a taxa de propofol, consumo de fentanil, tempo cirúrgico, extubação, alta anestésica e escore de sangramento. Houve redução média de 46% de na frequência cardíaca após administração de dexmedetomidina. Ao mesmo tempo que após indução a pressão arterial sistólica foi de 125 ±26 mmHg no GC comparada 148 ±42 mmHg em GDEX. Houve também, redução de 73% no consumo de fentanil e 29% na taxa de propofol. Ainda, o escore visual de sangramento foi maior no GDEX. Conclui- se que a associação da dexmedetomidina ao protocolo diminuiu a taxa de propofol e melhorou a analgesia transoperatória de cadelas submetidas à castração.

Background: Hemogasometric analysis is used in the interpretation of acid-base balance (ABB) and to access pulmonary ventilation. Already mixed venous oxygen saturation obtained at pulmonary artery correlates with tissue oxygenation. However, both samples can be difficult to access because of the difficulties in arterial and pulmonary catheterization. The aim of this study was to evaluate the feasibility of replacing the arterial and mixed venous bloods, the end tidal pressure of carbon dioxide (EtCO2) and central venous blood in the analysis of pulmonary ventilation, tissue oxygenation and ABB in dogs under different hemodynamic states.Material, Methods & Results: Nine dogs were used with an average weight of 19.6 ± 1.3 kg, anesthetized with isoflurane at 1.4 V% diluted on oxygen 60% (Baseline), and subsequently undergoing mechanical ventilation (MV) and the hypodinamic state (Hypo) with isoflurane at 3.5V% and mean arterial pressure (MAP) lower than 50 mmHg and hyperdynamic state (Hyper) by dobutamine infusion at 5 μg/kg/min and with MAP 30% higher than baseline. For each time allowed a 15 min of stabilization by each hemodynamic status. Simultaneously were collected samples of 0.6 mL of arterial blood by metatarsal artery, mixed and central venous blood by pulmonary artery and right atrium for hemogasometric analysis. To access lung function we correlated and compared the EtCO2 values obtained by gas analyzer with expired carbon dioxide pressure in the arterial blood (PaCO2), mixed venous blood (PmvCO2) and central venous blood (PcvCO2). For the interpretation of tissue oxygenation we correlated and compared the values of mixed (SmvO2) and central (ScvO2) venous oxygen saturation. For the acid-base balance we used the correlation of potencial hydrogen (pH); carbon dioxide pressure (PCO2); bicarbonate ion (HCO3-); base excess (BE); anion GAP (AG); sodium ions (Na+), chlorine ions (Cl-), potassium ions (K+) and ionized calcium (iCa) of arterial (a) mixed venous (mv) and central venous (CV) bloods. Statistical analysis was performed using ANOVA-RM followed by Dunnet test for differences between times and Tukey’s test for differences among the samples (P ≤ 0.05). Pearson correlation analysis was performed using linear regression and for comparison methods we used the Bland-Altman analysis The EtCO2 values correlated (r = 0.87) and were according to Bland-Altman analysis with PaCO2 values (mean difference of -1.6 ± 2,9 mmHg for PaCO2. There were no differences (P ≤ 0.05) from SmvO2 and ScvO2. ScvO2 correlated (r = 0.91) with SmvO2 at different hemodynamic states and with a mean difference of -0.4 ± 2.5%. Both venous bloods were correlated with the analysis of arterial blood acid-base balance and electrolytes in different hemodynamic states. However, the ionized calcium levels were 40% lower in arterial blood.Discussion: EtCO2 measurement depends of monitor technology and proper pulmonar ventilation and perfusion. In this study the limiting factor in replacing the PaCO2 hair EtCO2 was spontaneous ventilation because in this state pulmonary ventilation is compromissed. With the use of MV was possible get up similar results in the pulmonar function analysis using the EtCO2 and PaCO2. The use of central venous blood instead mixed venous blood at oxygen saturation analysis provided adequate estimate this parameter. This being easier and less invasive technique. ABB was possible with all samples with own reference values for venous and arterial samples. This is an interesting result for critical patients where the arterial sample is difficult. In electrolytes the sample was indifferent except for calcium because pH interfere in this values. It was conclude that the values of EtCO2 and central venous blood are correlated and can replace arterial and mixed venous bloods in the analysis of lung function, tissue oxygenation and acid base balance.